Yohimbine
TL;DR: Yohimbine (CAS 146-48-5) is a chemical compound with molecular formula C21H26N2O3 and molecular weight 354.19434 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
methyl (1S,15R,18S,19R,20S)-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate
Also Known As: Yohimbine, Yohimbin, Quebrachine, Quebrachin, Corynine
Application Areas
Top 5 of 17 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C21H26N2O3 |
| Molecular Weight | 354.19434 g/mol |
| XLogP | 2.9 |
| Topological Polar Surface Area (TPSA) | 65.6 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 354.19434 Da |
| Heavy Atoms | 26 |
| Complexity | 555.0 |
| Melting Point | 241 |
| Solubility | 3.48e-01 g/L |
| SMILES | COC(=O)[C@H]1[C@H](CC[C@@H]2[C@@H]1C[C@H]3C4=C(CCN3C2)C5=CC=CC=C5N4)O |
| InChIKey | BLGXFZZNTVWLAY-SCYLSFHTSA-N |
Product Description
Applications: Yohimbine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Yohimbine (CAS 146-48-5) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
Yohimbine is a pharmaceutical intermediate identified by CAS number 146-48-5 and the molecular formula C21H26N2O3 and a molecular weight of 354.19 g/mol. Physically, the compound has a solubility: 3.48e-01 g/L. It is also known as Yohimbine and Yohimbin.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Yohimbine
Property Insights of Yohimbine
The XLogP value of 2.9 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Yohimbine. The TPSA of 65.6 Ų falls within the moderate polarity range, balancing permeability and solubility for Yohimbine. Following Lipinski's Rule of Five, Yohimbine has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Yohimbine?
The CAS number of Yohimbine is 146-48-5.
What is the molecular formula of Yohimbine?
The molecular formula of Yohimbine is C21H26N2O3.
What is the molecular weight of Yohimbine?
The molecular weight of Yohimbine is 354.19434 g/mol.
What are the applications of Yohimbine?
Yohimbine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Yohimbine (CAS 146-48-5) with custom...
Where can I buy Yohimbine?
You can request a quote for Yohimbine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Yohimbine?
Yes, CoreyChem provides custom synthesis services for Yohimbine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.