8-Hydroxyquinoline
TL;DR: 8-Hydroxyquinoline (CAS 148-24-3) is a chemical compound with molecular formula C9H7NO and molecular weight 145.05276 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
quinolin-8-ol
Also Known As: 8-HYDROXYQUINOLINE, quinolin-8-ol, 8-quinolinol, Oxyquinoline, Oxine
Application Areas
Top 5 of 22 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C9H7NO |
| Molecular Weight | 145.05276 g/mol |
| XLogP | 2.0 |
| Topological Polar Surface Area (TPSA) | 33.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 0 |
| Exact Mass | 145.05276 Da |
| Heavy Atoms | 11 |
| Complexity | 138.0 |
| Melting Point | 169 °F (NTP, 1992) |
| Boiling Point | 513 °F at 760 mmHg (NTP, 1992) |
| Density | 1.034 at 408 °F (NTP, 1992) - Denser than water; will sink |
| Vapor Pressure | 0.0016 [mmHg] |
| Solubility | less than 1 mg/mL at 61 °F (NTP, 1992) |
| SMILES | C1=CC2=C(C(=C1)O)N=CC=C2 |
| InChIKey | MCJGNVYPOGVAJF-UHFFFAOYSA-N |
Product Description
Applications: 8-Hydroxyquinoline is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies 8-Hydroxyquinoline (CAS 148-24-3) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
A pharmaceutical intermediate supplied by CoreyChem, 8-Hydroxyquinoline (CAS 148-24-3) has the molecular formula C9H7NO and a molecular weight of 145.05 g/mol. Reported properties include a density of 1.034 at 408 °F (NTP, 1992) - Denser than water; will sink g/cm³, a solubility: less than 1 mg/mL at 61 °F (NTP, 1992). It is also known as 8-HYDROXYQUINOLINE and quinolin-8-ol.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of 8-Hydroxyquinoline
Property Insights of 8-Hydroxyquinoline
The XLogP value of 2.0 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 8-Hydroxyquinoline. With a topological polar surface area (TPSA) of 33.1 Ų, 8-Hydroxyquinoline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 8-Hydroxyquinoline has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 8-Hydroxyquinoline?
The CAS number of 8-Hydroxyquinoline is 148-24-3.
What is the molecular formula of 8-Hydroxyquinoline?
The molecular formula of 8-Hydroxyquinoline is C9H7NO.
What is the molecular weight of 8-Hydroxyquinoline?
The molecular weight of 8-Hydroxyquinoline is 145.05276 g/mol.
What are the applications of 8-Hydroxyquinoline?
8-Hydroxyquinoline is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies 8-Hydroxyquinoline (CAS 148-24-3)...
Where can I buy 8-Hydroxyquinoline?
You can request a quote for 8-Hydroxyquinoline directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 8-Hydroxyquinoline?
Yes, CoreyChem provides custom synthesis services for 8-Hydroxyquinoline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.