Trimethyl orthoformate
TL;DR: Trimethyl orthoformate (CAS 149-73-5) is a chemical compound with molecular formula C4H10O3 and molecular weight 106.062996 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
trimethoxymethane
Also Known As: Trimethoxymethane, TRIMETHYL ORTHOFORMATE, Methyl orthoformate, Methane, trimethoxy-, Methoxymethylal
Application Areas
Top 5 of 22 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C4H10O3 |
| Molecular Weight | 106.062996 g/mol |
| XLogP | 0.2 |
| Topological Polar Surface Area (TPSA) | 27.7 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 106.062996 Da |
| Heavy Atoms | 7 |
| Complexity | 28.0 |
| Boiling Point | 100.6 °C @ 760 MM HG |
| Density | 0.9676 @ 20 °C/4 °C |
| Vapor Pressure | 81.4 [mmHg] |
| Refractive Index | INDEX OF REFRACTION: 1.3773 @ 25 °C/D |
| Solubility | SOL IN ETHANOL, IN ETHER |
| SMILES | COC(OC)OC |
| InChIKey | PYOKUURKVVELLB-UHFFFAOYSA-N |
Product Description
Applications: Trimethyl orthoformate is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Trimethyl orthoformate (CAS 149-73-5) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
A heterocyclic building block supplied by CoreyChem, Trimethyl orthoformate (CAS 149-73-5) has the molecular formula C4H10O3 and a molecular weight of 106.06 g/mol. Reported properties include a density of 0.9676 @ 20 °C/4 °C g/cm³, a solubility: SOL IN ETHANOL, IN ETHER. It is also known as Trimethoxymethane and TRIMETHYL ORTHOFORMATE.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Trimethyl orthoformate
Property Insights of Trimethyl orthoformate
The XLogP value of 0.2 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Trimethyl orthoformate. With a topological polar surface area (TPSA) of 27.7 Ų, Trimethyl orthoformate exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Trimethyl orthoformate has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Trimethyl orthoformate?
The CAS number of Trimethyl orthoformate is 149-73-5.
What is the molecular formula of Trimethyl orthoformate?
The molecular formula of Trimethyl orthoformate is C4H10O3.
What is the molecular weight of Trimethyl orthoformate?
The molecular weight of Trimethyl orthoformate is 106.062996 g/mol.
What are the applications of Trimethyl orthoformate?
Trimethyl orthoformate is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Trimethyl orthoformate (CAS...
Where can I buy Trimethyl orthoformate?
You can request a quote for Trimethyl orthoformate directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Trimethyl orthoformate?
Yes, CoreyChem provides custom synthesis services for Trimethyl orthoformate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.