TL;DR: ro 32-0432 (CAS 151342-35-7) is a chemical compound with molecular formula C28H28N4O2 and molecular weight 452.22122 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
3-[(8S)-8-[(dimethylamino)methyl]-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methylindol-3-yl)pyrrole-2,5-dione
Also Known As: ro 32-0432, Ro-32-0432, Ro 32-0432 hydrochloride, Bisindolylmaleimide deriv. 18b, ro32-0432
Top 5 of 1 IPC patent classification(s) from the SureChEMBL global patent database.
| Molecular Formula | C28H28N4O2 |
| Molecular Weight | 452.22122 g/mol |
| XLogP | 3.4 |
| Topological Polar Surface Area (TPSA) | 59.3 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 452.22122 Da |
| Heavy Atoms | 34 |
| Complexity | 868.0 |
| SMILES | CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=C5C[C@H](CCN5C6=CC=CC=C64)CN(C)C |
| InChIKey | FXGHOAZJQNLNFD-KRWDZBQOSA-N |
The XLogP value of 3.4 indicates that ro 32-0432 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 59.3 Ų, ro 32-0432 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, ro 32-0432 has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
The CAS number of ro 32-0432 is 151342-35-7.
The molecular formula of ro 32-0432 is C28H28N4O2.
The molecular weight of ro 32-0432 is 452.22122 g/mol.
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