Dydrogesterone
TL;DR: Dydrogesterone (CAS 152-62-5) is a chemical compound with molecular formula C21H28O2 and molecular weight 312.20892 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(8S,9R,10S,13S,14S,17S)-17-acetyl-10,13-dimethyl-1,2,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-one
Also Known As: dydrogesterone, Isopregnenone, Hydrogesterone, Duphaston, Gynorest
Application Areas
Top 5 of 14 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C21H28O2 |
| Molecular Weight | 312.20892 g/mol |
| XLogP | 3.8 |
| Topological Polar Surface Area (TPSA) | 34.1 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 312.20892 Da |
| Heavy Atoms | 23 |
| Complexity | 628.0 |
| Melting Point | 168-169 |
| Solubility | Soluble in acetone, chloroform (1 in 2), ethanol (1 in 40) and diethyl ether (1 in 200); slightly soluble in fixed oils; sparingly soluble in methanol. |
| SMILES | CC(=O)[C@H]1CC[C@@H]2[C@@]1(CC[C@@H]3[C@H]2C=CC4=CC(=O)CC[C@@]34C)C |
| InChIKey | JGMOKGBVKVMRFX-HQZYFCCVSA-N |
Product Description
Applications: Dydrogesterone is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Dydrogesterone is a pharmaceutical intermediate identified by CAS number 152-62-5 and the molecular formula C21H28O2 and a molecular weight of 312.21 g/mol. Physically, the compound has a solubility: Soluble in acetone, chloroform (1 in 2), ethanol (1 in 40) and diethyl ether (1 in 200); slightly soluble in fixed oils; sparingly soluble in methanol. Synonyms include dydrogesterone and Isopregnenone.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Dydrogesterone
Property Insights of Dydrogesterone
The XLogP value of 3.8 indicates that Dydrogesterone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 34.1 Ų, Dydrogesterone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Dydrogesterone has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Dydrogesterone?
The CAS number of Dydrogesterone is 152-62-5.
What is the molecular formula of Dydrogesterone?
The molecular formula of Dydrogesterone is C21H28O2.
What is the molecular weight of Dydrogesterone?
The molecular weight of Dydrogesterone is 312.20892 g/mol.
What are the applications of Dydrogesterone?
Dydrogesterone is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Dydrogesterone?
You can request a quote for Dydrogesterone directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Dydrogesterone?
Yes, CoreyChem provides custom synthesis services for Dydrogesterone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.