Nolpitantium chloride
TL;DR: Nolpitantium chloride (CAS 153050-21-6) is a chemical compound with molecular formula C37H45Cl3N2O2 and molecular weight 654.25464 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-[(3S)-3-(3,4-dichlorophenyl)-3-[2-(4-phenyl-1-azoniabicyclo[2.2.2]octan-1-yl)ethyl]piperidin-1-yl]-2-(3-propan-2-yloxyphenyl)ethanone chloride
Also Known As: Nolpitantium, Nolpitantium chloride, SR 140333, SR 140333A, SR 140,333
Application Areas
Top 5 of 1 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C37H45Cl3N2O2 |
| Molecular Weight | 654.25464 g/mol |
| XLogP | 5.23 |
| Topological Polar Surface Area (TPSA) | 29.5 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 9 |
| Exact Mass | 654.25464 Da |
| Heavy Atoms | 44 |
| Complexity | 913.0 |
| SMILES | CC(C)OC1=CC=CC(=C1)CC(=O)N2CCC[C@](C2)(CC[N+]34CCC(CC3)(CC4)C5=CC=CC=C5)C6=CC(=C(C=C6)Cl)Cl.[Cl-] |
| InChIKey | NQHFSECYQAQZBN-LSYPWIJNSA-M |
Chemical Property Profile of Nolpitantium chloride
Property Insights of Nolpitantium chloride
The XLogP value of 5.23 indicates that Nolpitantium chloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 29.5 Ų, Nolpitantium chloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Nolpitantium chloride has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of Nolpitantium chloride?
The CAS number of Nolpitantium chloride is 153050-21-6.
What is the molecular formula of Nolpitantium chloride?
The molecular formula of Nolpitantium chloride is C37H45Cl3N2O2.
What is the molecular weight of Nolpitantium chloride?
The molecular weight of Nolpitantium chloride is 654.25464 g/mol.
Where can I buy Nolpitantium chloride?
You can request a quote for Nolpitantium chloride directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Nolpitantium chloride?
Yes, CoreyChem provides custom synthesis services for Nolpitantium chloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.