Hydroxyphenylacetic acid
TL;DR: Hydroxyphenylacetic acid (CAS 156-38-7) is a chemical compound with molecular formula C8H8O3 and molecular weight 152.04735 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-(4-hydroxyphenyl)acetic acid
Also Known As: 4-hydroxyphenylacetic acid, 2-(4-hydroxyphenyl)acetic acid, p-hydroxyphenylacetic acid, 4-hydroxyphenylacetate, (4-Hydroxyphenyl)acetic acid
Application Areas
Top 5 of 22 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C8H8O3 |
| Molecular Weight | 152.04735 g/mol |
| XLogP | 0.8 |
| Topological Polar Surface Area (TPSA) | 57.5 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 152.04735 Da |
| Heavy Atoms | 11 |
| Complexity | 136.0 |
| Melting Point | 148 - 150 °C |
| Vapor Pressure | 0.0000555 [mmHg] |
| Solubility | 60.7 mg/mL |
| SMILES | C1=CC(=CC=C1CC(=O)O)O |
| InChIKey | XQXPVVBIMDBYFF-UHFFFAOYSA-N |
Product Description
Applications: Hydroxyphenylacetic acid is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Hydroxyphenylacetic acid is a pharmaceutical intermediate identified by CAS number 156-38-7 and the molecular formula C8H8O3 and a molecular weight of 152.05 g/mol. Physically, the compound has a solubility: 60.7 mg/mL. Synonyms include 4-hydroxyphenylacetic acid and 2-(4-hydroxyphenyl)acetic acid.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Hydroxyphenylacetic acid
Property Insights of Hydroxyphenylacetic acid
The XLogP value of 0.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Hydroxyphenylacetic acid. With a topological polar surface area (TPSA) of 57.5 Ų, Hydroxyphenylacetic acid exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Hydroxyphenylacetic acid has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Hydroxyphenylacetic acid?
The CAS number of Hydroxyphenylacetic acid is 156-38-7.
What is the molecular formula of Hydroxyphenylacetic acid?
The molecular formula of Hydroxyphenylacetic acid is C8H8O3.
What is the molecular weight of Hydroxyphenylacetic acid?
The molecular weight of Hydroxyphenylacetic acid is 152.04735 g/mol.
What are the applications of Hydroxyphenylacetic acid?
Hydroxyphenylacetic acid is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Hydroxyphenylacetic acid?
You can request a quote for Hydroxyphenylacetic acid directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Hydroxyphenylacetic acid?
Yes, CoreyChem provides custom synthesis services for Hydroxyphenylacetic acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.