4-Ethoxyaniline
TL;DR: 4-Ethoxyaniline (CAS 156-43-4) is a chemical compound with molecular formula C8H11NO and molecular weight 137.08406 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
4-ethoxyaniline
Also Known As: p-Phenetidine, 4-ETHOXYANILINE, Phenetidine, 4-Aminophenetole, p-Ethoxyaniline
Application Areas
Top 5 of 22 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C8H11NO |
| Molecular Weight | 137.08406 g/mol |
| XLogP | 1.2 |
| Topological Polar Surface Area (TPSA) | 35.3 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 137.08406 Da |
| Heavy Atoms | 10 |
| Complexity | 87.0 |
| Melting Point | 36 to 39 °F (NTP, 1992) |
| Boiling Point | 482 °F at 760 mmHg (NTP, 1992) |
| Density | 1.0652 at 61 °F (NTP, 1992) - Denser than water; will sink |
| Flash Point | 240 °F (NTP, 1992) |
| Vapor Pressure | 3.48 mmHg at 77 °F (NTP, 1992) |
| Solubility | 5 to 10 mg/mL at 68 °F (NTP, 1992) |
| SMILES | CCOC1=CC=C(C=C1)N |
| InChIKey | IMPPGHMHELILKG-UHFFFAOYSA-N |
Product Description
Applications: 4-Ethoxyaniline is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies 4-Ethoxyaniline (CAS 156-43-4) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
4-Ethoxyaniline (CAS 156-43-4) is a heterocyclic building block with the molecular formula C8H11NO and a molecular weight of 137.08 g/mol. Key physical properties include a density of 1.0652 at 61 °F (NTP, 1992) - Denser than water; will sink g/cm³, a solubility: 5 to 10 mg/mL at 68 °F (NTP, 1992). It is also known as p-Phenetidine and 4-ETHOXYANILINE.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of 4-Ethoxyaniline
Property Insights of 4-Ethoxyaniline
The XLogP value of 1.2 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 4-Ethoxyaniline. With a topological polar surface area (TPSA) of 35.3 Ų, 4-Ethoxyaniline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-Ethoxyaniline has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 4-Ethoxyaniline?
The CAS number of 4-Ethoxyaniline is 156-43-4.
What is the molecular formula of 4-Ethoxyaniline?
The molecular formula of 4-Ethoxyaniline is C8H11NO.
What is the molecular weight of 4-Ethoxyaniline?
The molecular weight of 4-Ethoxyaniline is 137.08406 g/mol.
What are the applications of 4-Ethoxyaniline?
4-Ethoxyaniline is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies 4-Ethoxyaniline (CAS 156-43-4) with...
Where can I buy 4-Ethoxyaniline?
You can request a quote for 4-Ethoxyaniline directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 4-Ethoxyaniline?
Yes, CoreyChem provides custom synthesis services for 4-Ethoxyaniline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.