Dropropizine
TL;DR: Dropropizine (CAS 17692-31-8) is a chemical compound with molecular formula C13H20N2O2 and molecular weight 236.15248 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
3-(4-phenylpiperazin-1-yl)propane-1,2-diol
Also Known As: dropropizine, Dipropizine, Catabex, Katril, Levodropropizine
Application Areas
Top 5 of 8 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C13H20N2O2 |
| Molecular Weight | 236.15248 g/mol |
| XLogP | 0.6 |
| Topological Polar Surface Area (TPSA) | 46.9 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 236.15248 Da |
| Heavy Atoms | 17 |
| Complexity | 211.0 |
| Solubility | >35.4 [ug/mL] (The mean of the results at pH 7.4) |
| SMILES | C1CN(CCN1CC(CO)O)C2=CC=CC=C2 |
| InChIKey | PTVWPYVOOKLBCG-UHFFFAOYSA-N |
Product Description
Applications: Dropropizine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
A pharmaceutical intermediate supplied by CoreyChem, Dropropizine (CAS 17692-31-8) has the molecular formula C13H20N2O2 and a molecular weight of 236.15 g/mol. Reported properties include a solubility: >35.4 [ug/mL] (The mean of the results at pH 7.4). Synonyms include dropropizine and Dipropizine.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Dropropizine
Property Insights of Dropropizine
The XLogP value of 0.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Dropropizine. With a topological polar surface area (TPSA) of 46.9 Ų, Dropropizine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Dropropizine has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Dropropizine?
The CAS number of Dropropizine is 17692-31-8.
What is the molecular formula of Dropropizine?
The molecular formula of Dropropizine is C13H20N2O2.
What is the molecular weight of Dropropizine?
The molecular weight of Dropropizine is 236.15248 g/mol.
What are the applications of Dropropizine?
Dropropizine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Dropropizine?
You can request a quote for Dropropizine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Dropropizine?
Yes, CoreyChem provides custom synthesis services for Dropropizine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.