FK506
TL;DR: FK506 (CAS 186452-09-5) is a chemical compound with molecular formula C20H28N2O4 and molecular weight 360.2049 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
他克莫司
3-pyridin-3-ylpropyl 1-(3,3-dimethyl-2-oxopentanoyl)pyrrolidine-2-carboxylate
Also Known As: FK506, GPI 1046, 4CH-016330, 6477-EP1441224A2, 6477-EP2269651A2
Application Areas
Top 5 of 16 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C20H28N2O4 |
| Molecular Weight | 360.2049 g/mol |
| XLogP | 3.1 |
| Topological Polar Surface Area (TPSA) | 76.6 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 9 |
| Exact Mass | 360.2049 Da |
| Heavy Atoms | 26 |
| Complexity | 518.0 |
| SMILES | CCC(C)(C)C(=O)C(=O)N1CCCC1C(=O)OCCCC2=CN=CC=C2 |
| InChIKey | OQAHHWOPVDDWHD-UHFFFAOYSA-N |
Chemical Property Profile of FK506
Property Insights of FK506
The XLogP value of 3.1 indicates that FK506 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 76.6 Ų falls within the moderate polarity range, balancing permeability and solubility for FK506. Following Lipinski's Rule of Five, FK506 has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of FK506?
The CAS number of FK506 is 186452-09-5.
What is the molecular formula of FK506?
The molecular formula of FK506 is C20H28N2O4.
What is the molecular weight of FK506?
The molecular weight of FK506 is 360.2049 g/mol.
Where can I buy FK506?
You can request a quote for FK506 directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for FK506?
Yes, CoreyChem provides custom synthesis services for FK506 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.