![3-[(2,4,6-trimethoxyphenyl)methylidene]-1H-indol-2-one structure](/static/products/1866/186611-52-9.webp)
3-[(2,4,6-trimethoxyphenyl)methylidene]-1H-indol-2-one
TL;DR: 3-[(2,4,6-trimethoxyphenyl)methylidene]-1H-indol-2-one (CAS 186611-52-9) is a chemical compound with molecular formula C18H17NO4 and molecular weight 311.11575 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
3-[(2,4,6-trimethoxyphenyl)methylidene]-1H-indol-2-one
Also Known As: ic261, Maybridge3_000754, IC 261, IC261, SU5607, IC-261(SU-5607)
Application Areas
Top 5 of 4 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C18H17NO4 |
| Molecular Weight | 311.11575 g/mol |
| XLogP | 2.8 |
| Topological Polar Surface Area (TPSA) | 56.8 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 311.11575 Da |
| Heavy Atoms | 23 |
| Complexity | 450.0 |
| SMILES | COC1=CC(=C(C(=C1)OC)C=C2C3=CC=CC=C3NC2=O)OC |
| InChIKey | JBJYTZXCZDNOJW-UHFFFAOYSA-N |
Product Description
Applications: 3-[(2,4,6-trimethoxyphenyl)methylidene]-1H-indol-2-one is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies 3-[(2,4,6-trimethoxyphenyl)methylidene]-1H-indol-2-one (CAS 186611-52-9) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
3-[(2,4,6-trimethoxyphenyl)methylidene]-1H-indol-2-one is a pharmaceutical intermediate identified by CAS number 186611-52-9 and the molecular formula C18H17NO4 and a molecular weight of 311.12 g/mol. It is also known as ic261 and Maybridge3_000754.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of 3-[(2,4,6-trimethoxyphenyl)methylidene]-1H-indol-2-one
Property Insights of 3-[(2,4,6-trimethoxyphenyl)methylidene]-1H-indol-2-one
The XLogP value of 2.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 3-[(2,4,6-trimethoxyphenyl)methylidene]-1H-indol-2-one. With a topological polar surface area (TPSA) of 56.8 Ų, 3-[(2,4,6-trimethoxyphenyl)methylidene]-1H-indol-2-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 3-[(2,4,6-trimethoxyphenyl)methylidene]-1H-indol-2-one has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 3-[(2,4,6-trimethoxyphenyl)methylidene]-1H-indol-2-one?
The CAS number of 3-[(2,4,6-trimethoxyphenyl)methylidene]-1H-indol-2-one is 186611-52-9.
What is the molecular formula of 3-[(2,4,6-trimethoxyphenyl)methylidene]-1H-indol-2-one?
The molecular formula of 3-[(2,4,6-trimethoxyphenyl)methylidene]-1H-indol-2-one is C18H17NO4.
What is the molecular weight of 3-[(2,4,6-trimethoxyphenyl)methylidene]-1H-indol-2-one?
The molecular weight of 3-[(2,4,6-trimethoxyphenyl)methylidene]-1H-indol-2-one is 311.11575 g/mol.
What are the applications of 3-[(2,4,6-trimethoxyphenyl)methylidene]-1H-indol-2-one?
3-[(2,4,6-trimethoxyphenyl)methylidene]-1H-indol-2-one is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies...
Where can I buy 3-[(2,4,6-trimethoxyphenyl)methylidene]-1H-indol-2-one?
You can request a quote for 3-[(2,4,6-trimethoxyphenyl)methylidene]-1H-indol-2-one directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 3-[(2,4,6-trimethoxyphenyl)methylidene]-1H-indol-2-one?
Yes, CoreyChem provides custom synthesis services for 3-[(2,4,6-trimethoxyphenyl)methylidene]-1H-indol-2-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.