Lopinavir
TL;DR: Lopinavir (CAS 192725-17-0) is a chemical compound with molecular formula C37H48N4O5 and molecular weight 628.3625 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N-[5-[[2-(2,6-dimethylphenoxy)acetyl]amino]-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanamide
Also Known As: Lopinavir, Aluvia, Lopinavir-d8, (2R,4S,5S)-Lopinavir, Lopinavir [USAN:INN:BAN]
Technical Specifications
| Molecular Formula | C37H48N4O5 |
| Molecular Weight | 628.3625 g/mol |
| XLogP | 5.9 |
| Topological Polar Surface Area (TPSA) | 120.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 15 |
| Exact Mass | 628.3625 Da |
| Heavy Atoms | 46 |
| Complexity | 940.0 |
| SMILES | CC1=C(C(=CC=C1)C)OCC(=O)NC(CC2=CC=CC=C2)C(CC(CC3=CC=CC=C3)NC(=O)C(C(C)C)N4CCCNC4=O)O |
| InChIKey | KJHKTHWMRKYKJE-UHFFFAOYSA-N |
Chemical Property Profile of Lopinavir
Property Insights of Lopinavir
The XLogP value of 5.9 indicates that Lopinavir is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 120.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Lopinavir. Following Lipinski's Rule of Five, Lopinavir has 4 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of Lopinavir?
The CAS number of Lopinavir is 192725-17-0.
What is the molecular formula of Lopinavir?
The molecular formula of Lopinavir is C37H48N4O5.
What is the molecular weight of Lopinavir?
The molecular weight of Lopinavir is 628.3625 g/mol.
Where can I buy Lopinavir?
You can request a quote for Lopinavir directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Lopinavir?
Yes, CoreyChem provides custom synthesis services for Lopinavir and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.