Propofol
TL;DR: Propofol (CAS 2078-54-8) is a chemical compound with molecular formula C12H18O and molecular weight 178.13577 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2,6-di(propan-2-yl)phenol
Also Known As: propofol, 2,6-DIISOPROPYLPHENOL, Diprivan, Disoprofol, Disoprivan
Application Areas
Top 5 of 22 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C12H18O |
| Molecular Weight | 178.13577 g/mol |
| XLogP | 3.8 |
| Topological Polar Surface Area (TPSA) | 20.2 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 2 |
| Exact Mass | 178.13577 Da |
| Heavy Atoms | 13 |
| Complexity | 135.0 |
| Melting Point | 18 |
| Boiling Point | 256 |
| Density | 0.955 g/cu cm @ 20 °C |
| Refractive Index | Index of refraction (sodium light): 1.5134 @ 20 °C; 1.5111 @ 25 °C. |
| Solubility | 124 |
| SMILES | CC(C)C1=C(C(=CC=C1)C(C)C)O |
| InChIKey | OLBCVFGFOZPWHH-UHFFFAOYSA-N |
Product Description
Applications: Propofol is used in pharmaceutical synthesis routes and API production, as well as polymer chemistry and functional materials synthesis. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Propofol (CAS 2078-54-8) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
A pharmaceutical intermediate supplied by CoreyChem, Propofol (CAS 2078-54-8) has the molecular formula C12H18O and a molecular weight of 178.14 g/mol. Reported properties include a density of 0.955 g/cu cm @ 20 °C g/cm³, a solubility: 124. It is also known as propofol and 2,6-DIISOPROPYLPHENOL.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Propofol
Property Insights of Propofol
The XLogP value of 3.8 indicates that Propofol is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 20.2 Ų, Propofol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Propofol has 1 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Propofol?
The CAS number of Propofol is 2078-54-8.
What is the molecular formula of Propofol?
The molecular formula of Propofol is C12H18O.
What is the molecular weight of Propofol?
The molecular weight of Propofol is 178.13577 g/mol.
What are the applications of Propofol?
Propofol is used in pharmaceutical synthesis routes and API production, as well as polymer chemistry and functional materials synthesis. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Propofol (CAS 2078-54-8) with custom synthesis available from...
Where can I buy Propofol?
You can request a quote for Propofol directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Propofol?
Yes, CoreyChem provides custom synthesis services for Propofol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.