Berberine
TL;DR: Berberine (CAS 2086-83-1) is a chemical compound with molecular formula C20H18NO4+ and molecular weight 336.1236 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
16,17-dimethoxy-5,7-dioxa-13-azoniapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-1(13),2,4(8),9,14,16,18,20-octaene
Also Known As: berberine, Umbellatine, Berberin, Berbericine, Umbellatin
Application Areas
Top 5 of 20 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C20H18NO4+ |
| Molecular Weight | 336.1236 g/mol |
| XLogP | 3.6 |
| Topological Polar Surface Area (TPSA) | 40.8 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 336.1236 Da |
| Heavy Atoms | 25 |
| Complexity | 488.0 |
| Melting Point | 145 |
| SMILES | COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC5=C(C=C4CC3)OCO5)OC |
| InChIKey | YBHILYKTIRIUTE-UHFFFAOYSA-N |
Product Description
Applications: Berberine is used in pharmaceutical synthesis routes and API production, as well as biotechnology workflows and life-science research. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Berberine is a pharmaceutical intermediate identified by CAS number 2086-83-1 and the molecular formula C20H18NO4+ and a molecular weight of 336.12 g/mol. Synonyms include berberine and Umbellatine.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Berberine
Property Insights of Berberine
The XLogP value of 3.6 indicates that Berberine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 40.8 Ų, Berberine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Berberine has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Berberine?
The CAS number of Berberine is 2086-83-1.
What is the molecular formula of Berberine?
The molecular formula of Berberine is C20H18NO4+.
What is the molecular weight of Berberine?
The molecular weight of Berberine is 336.1236 g/mol.
What are the applications of Berberine?
Berberine is used in pharmaceutical synthesis routes and API production, as well as biotechnology workflows and life-science research. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton...
Where can I buy Berberine?
You can request a quote for Berberine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Berberine?
Yes, CoreyChem provides custom synthesis services for Berberine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.