4-(3-Hydroxyanilino)-6,7-Dimethoxyquinazoline
TL;DR: 4-(3-Hydroxyanilino)-6,7-Dimethoxyquinazoline (CAS 211555-08-7) is a chemical compound with molecular formula C16H15N3O3 and molecular weight 297.11133 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
3-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol
Also Known As: whi-p180, 3-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol, 4btk, WHI-P180, Hydrochloride, JANEX 3
Application Areas
Top 5 of 2 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C16H15N3O3 |
| Molecular Weight | 297.11133 g/mol |
| XLogP | 3.0 |
| Topological Polar Surface Area (TPSA) | 76.5 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 4 |
| Exact Mass | 297.11133 Da |
| Heavy Atoms | 22 |
| Complexity | 358.0 |
| SMILES | COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)O)OC |
| InChIKey | BNDYIYYKEIXHNK-UHFFFAOYSA-N |
Product Description
Applications: 4-(3-Hydroxyanilino)-6,7-Dimethoxyquinazoline is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
A pharmaceutical intermediate supplied by CoreyChem, 4-(3-Hydroxyanilino)-6,7-Dimethoxyquinazoline (CAS 211555-08-7) has the molecular formula C16H15N3O3 and a molecular weight of 297.11 g/mol. Synonyms include whi-p180 and 3-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of 4-(3-Hydroxyanilino)-6,7-Dimethoxyquinazoline
Property Insights of 4-(3-Hydroxyanilino)-6,7-Dimethoxyquinazoline
The XLogP value of 3.0 indicates that 4-(3-Hydroxyanilino)-6,7-Dimethoxyquinazoline is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 76.5 Ų falls within the moderate polarity range, balancing permeability and solubility for 4-(3-Hydroxyanilino)-6,7-Dimethoxyquinazoline. Following Lipinski's Rule of Five, 4-(3-Hydroxyanilino)-6,7-Dimethoxyquinazoline has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 4-(3-Hydroxyanilino)-6,7-Dimethoxyquinazoline?
The CAS number of 4-(3-Hydroxyanilino)-6,7-Dimethoxyquinazoline is 211555-08-7.
What is the molecular formula of 4-(3-Hydroxyanilino)-6,7-Dimethoxyquinazoline?
The molecular formula of 4-(3-Hydroxyanilino)-6,7-Dimethoxyquinazoline is C16H15N3O3.
What is the molecular weight of 4-(3-Hydroxyanilino)-6,7-Dimethoxyquinazoline?
The molecular weight of 4-(3-Hydroxyanilino)-6,7-Dimethoxyquinazoline is 297.11133 g/mol.
What are the applications of 4-(3-Hydroxyanilino)-6,7-Dimethoxyquinazoline?
4-(3-Hydroxyanilino)-6,7-Dimethoxyquinazoline is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as...
Where can I buy 4-(3-Hydroxyanilino)-6,7-Dimethoxyquinazoline?
You can request a quote for 4-(3-Hydroxyanilino)-6,7-Dimethoxyquinazoline directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 4-(3-Hydroxyanilino)-6,7-Dimethoxyquinazoline?
Yes, CoreyChem provides custom synthesis services for 4-(3-Hydroxyanilino)-6,7-Dimethoxyquinazoline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.