Tofisopam
TL;DR: Tofisopam (CAS 22345-47-7) is a chemical compound with molecular formula C22H26N2O4 and molecular weight 382.18927 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-(3,4-dimethoxyphenyl)-5-ethyl-7,8-dimethoxy-4-methyl-5H-2,3-benzodiazepine
Also Known As: tofisopam, Grandaxin, Emandaxin, tofizopam, Tofisopamum
Application Areas
Top 5 of 13 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C22H26N2O4 |
| Molecular Weight | 382.18927 g/mol |
| XLogP | 3.2 |
| Topological Polar Surface Area (TPSA) | 61.6 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 6 |
| Exact Mass | 382.18927 Da |
| Heavy Atoms | 28 |
| Complexity | 579.0 |
| Melting Point | 156.5 |
| SMILES | CCC1C(=NN=C(C2=CC(=C(C=C12)OC)OC)C3=CC(=C(C=C3)OC)OC)C |
| InChIKey | RUJBDQSFYCKFAA-UHFFFAOYSA-N |
Product Description
Applications: Tofisopam is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Tofisopam (CAS 22345-47-7) is a pharmaceutical intermediate with the molecular formula C22H26N2O4 and a molecular weight of 382.19 g/mol. Synonyms include tofisopam and Grandaxin.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Tofisopam
Property Insights of Tofisopam
The XLogP value of 3.2 indicates that Tofisopam is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 61.6 Ų falls within the moderate polarity range, balancing permeability and solubility for Tofisopam. Following Lipinski's Rule of Five, Tofisopam has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Tofisopam?
The CAS number of Tofisopam is 22345-47-7.
What is the molecular formula of Tofisopam?
The molecular formula of Tofisopam is C22H26N2O4.
What is the molecular weight of Tofisopam?
The molecular weight of Tofisopam is 382.18927 g/mol.
What are the applications of Tofisopam?
Tofisopam is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Tofisopam?
You can request a quote for Tofisopam directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Tofisopam?
Yes, CoreyChem provides custom synthesis services for Tofisopam and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.