Bufexamac
TL;DR: Bufexamac (CAS 2438-72-4) is a chemical compound with molecular formula C12H17NO3 and molecular weight 223.12085 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-(4-butoxyphenyl)-N-hydroxyacetamide
Also Known As: bufexamac, Bufexamic acid, Parfenac, Anderm, Droxaryl
Application Areas
Top 5 of 17 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C12H17NO3 |
| Molecular Weight | 223.12085 g/mol |
| XLogP | 1.9 |
| Topological Polar Surface Area (TPSA) | 58.6 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 6 |
| Exact Mass | 223.12085 Da |
| Heavy Atoms | 16 |
| Complexity | 200.0 |
| Melting Point | 153 |
| Solubility | Immiscible |
| SMILES | CCCCOC1=CC=C(C=C1)CC(=O)NO |
| InChIKey | MXJWRABVEGLYDG-UHFFFAOYSA-N |
Product Description
Applications: Bufexamac is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
A pharmaceutical intermediate supplied by CoreyChem, Bufexamac (CAS 2438-72-4) has the molecular formula C12H17NO3 and a molecular weight of 223.12 g/mol. Reported properties include a solubility: Immiscible. Synonyms include bufexamac and Bufexamic acid.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Bufexamac
Property Insights of Bufexamac
The XLogP value of 1.9 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Bufexamac. With a topological polar surface area (TPSA) of 58.6 Ų, Bufexamac exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Bufexamac has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Bufexamac?
The CAS number of Bufexamac is 2438-72-4.
What is the molecular formula of Bufexamac?
The molecular formula of Bufexamac is C12H17NO3.
What is the molecular weight of Bufexamac?
The molecular weight of Bufexamac is 223.12085 g/mol.
What are the applications of Bufexamac?
Bufexamac is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Bufexamac?
You can request a quote for Bufexamac directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Bufexamac?
Yes, CoreyChem provides custom synthesis services for Bufexamac and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.