Gossypol
TL;DR: Gossypol (CAS 303-45-7) is a chemical compound with molecular formula C30H30O8 and molecular weight 518.1941 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
7-(8-formyl-1,6,7-trihydroxy-3-methyl-5-propan-2-ylnaphthalen-2-yl)-2,3,8-trihydroxy-6-methyl-4-propan-2-ylnaphthalene-1-carbaldehyde
Also Known As: gossypol, Pogosin, (-)-Gossypol, Tash 1, (+)-Gossypol
Application Areas
Top 5 of 20 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C30H30O8 |
| Molecular Weight | 518.1941 g/mol |
| XLogP | 6.9 |
| Topological Polar Surface Area (TPSA) | 156.0 Ų |
| Hydrogen Bond Donors | 6 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 5 |
| Exact Mass | 518.1941 Da |
| Heavy Atoms | 38 |
| Complexity | 780.0 |
| Melting Point | 184 °C (from ether); 199 °C (from chloroform); 214 °C (from ligroin) |
| Solubility | Very soluble in methanol, ethanol, cold dioxane, diethylene glucol, ether, ethyl acetate, acetone, carbon tetrachloride, pyridine, chloroform, DMF, lipds. Freely soluble (with slow desomposition) in dilute aqueous solutions of ammonia and sodium carbonate. Slightly soluble in glycerol, cyclohexane. Insoluble in water. |
| SMILES | CC1=CC2=C(C(=C(C(=C2C(C)C)O)O)C=O)C(=C1C3=C(C4=C(C=C3C)C(=C(C(=C4C=O)O)O)C(C)C)O)O |
| InChIKey | QBKSWRVVCFFDOT-UHFFFAOYSA-N |
Product Description
Applications: Gossypol is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Gossypol (CAS 303-45-7) is a pharmaceutical intermediate with the molecular formula C30H30O8 and a molecular weight of 518.19 g/mol. Key physical properties include a solubility: Very soluble in methanol, ethanol, cold dioxane, diethylene glucol, ether, ethyl acetate, acetone, carbon tetrachloride, pyridine, chloroform, DMF, lipds. Freely soluble (with slow desomposition) in dilute aqueous solutions of ammonia and sodium carbonate. Slightly soluble in glycerol, cyclohexane. Insoluble in water. Synonyms include gossypol and Pogosin.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Gossypol
Property Insights of Gossypol
The XLogP value of 6.9 indicates that Gossypol is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 156.0 Ų indicates high polarity, suggesting Gossypol may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Gossypol has 6 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of Gossypol?
The CAS number of Gossypol is 303-45-7.
What is the molecular formula of Gossypol?
The molecular formula of Gossypol is C30H30O8.
What is the molecular weight of Gossypol?
The molecular weight of Gossypol is 518.1941 g/mol.
What are the applications of Gossypol?
Gossypol is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Gossypol?
You can request a quote for Gossypol directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Gossypol?
Yes, CoreyChem provides custom synthesis services for Gossypol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.