4-Amino-1-pentofuranosyl-1,3,5-triazin-2(1H)-one
TL;DR: 4-Amino-1-pentofuranosyl-1,3,5-triazin-2(1H)-one (CAS 320-67-2) is a chemical compound with molecular formula C8H12N4O5 and molecular weight 244.08076 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
4-amino-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one
Also Known As: 5-azacytidine, Azacitidine, Ladakamycin, Azacytidine, Fazarabina
Application Areas
Top 5 of 1 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C8H12N4O5 |
| Molecular Weight | 244.08076 g/mol |
| XLogP | -2.2 |
| Topological Polar Surface Area (TPSA) | 141.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 244.08076 Da |
| Heavy Atoms | 17 |
| Complexity | 384.0 |
| SMILES | C1=NC(=NC(=O)N1C2C(C(C(O2)CO)O)O)N |
| InChIKey | NMUSYJAQQFHJEW-UHFFFAOYSA-N |
Product Description
Applications: 4-Amino-1-pentofuranosyl-1,3,5-triazin-2(1H)-one is used in pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
4-Amino-1-pentofuranosyl-1,3,5-triazin-2(1H)-one is a pharmaceutical intermediate identified by CAS number 320-67-2 and the molecular formula C8H12N4O5 and a molecular weight of 244.08 g/mol. Synonyms include 5-azacytidine and Azacitidine.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of 4-Amino-1-pentofuranosyl-1,3,5-triazin-2(1H)-one
Property Insights of 4-Amino-1-pentofuranosyl-1,3,5-triazin-2(1H)-one
The XLogP value of -2.2 indicates that 4-Amino-1-pentofuranosyl-1,3,5-triazin-2(1H)-one is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 141.0 Ų indicates high polarity, suggesting 4-Amino-1-pentofuranosyl-1,3,5-triazin-2(1H)-one may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 4-Amino-1-pentofuranosyl-1,3,5-triazin-2(1H)-one has 4 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 4-Amino-1-pentofuranosyl-1,3,5-triazin-2(1H)-one?
The CAS number of 4-Amino-1-pentofuranosyl-1,3,5-triazin-2(1H)-one is 320-67-2.
What is the molecular formula of 4-Amino-1-pentofuranosyl-1,3,5-triazin-2(1H)-one?
The molecular formula of 4-Amino-1-pentofuranosyl-1,3,5-triazin-2(1H)-one is C8H12N4O5.
What is the molecular weight of 4-Amino-1-pentofuranosyl-1,3,5-triazin-2(1H)-one?
The molecular weight of 4-Amino-1-pentofuranosyl-1,3,5-triazin-2(1H)-one is 244.08076 g/mol.
What are the applications of 4-Amino-1-pentofuranosyl-1,3,5-triazin-2(1H)-one?
4-Amino-1-pentofuranosyl-1,3,5-triazin-2(1H)-one is used in pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full...
Where can I buy 4-Amino-1-pentofuranosyl-1,3,5-triazin-2(1H)-one?
You can request a quote for 4-Amino-1-pentofuranosyl-1,3,5-triazin-2(1H)-one directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 4-Amino-1-pentofuranosyl-1,3,5-triazin-2(1H)-one?
Yes, CoreyChem provides custom synthesis services for 4-Amino-1-pentofuranosyl-1,3,5-triazin-2(1H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.