D-Proline
TL;DR: D-Proline (CAS 344-25-2) is a chemical compound with molecular formula C5H9NO2 and molecular weight 115.06333 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(2R)-pyrrolidine-2-carboxylic acid
Also Known As: D-proline, proline, H-D-Pro-OH, (R)-pyrrolidine-2-carboxylic acid, D-Prolin
Application Areas
Top 5 of 15 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C5H9NO2 |
| Molecular Weight | 115.06333 g/mol |
| XLogP | -2.5 |
| Topological Polar Surface Area (TPSA) | 49.3 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 115.06333 Da |
| Heavy Atoms | 8 |
| Complexity | 103.0 |
| Melting Point | 221 °C |
| SMILES | C1C[C@@H](NC1)C(=O)O |
| InChIKey | ONIBWKKTOPOVIA-SCSAIBSYSA-N |
Product Description
Applications: D-Proline is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies D-Proline (CAS 344-25-2) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
A pharmaceutical intermediate supplied by CoreyChem, D-Proline (CAS 344-25-2) has the molecular formula C5H9NO2 and a molecular weight of 115.06 g/mol. It is also known as D-proline and proline.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of D-Proline
Property Insights of D-Proline
The XLogP value of -2.5 indicates that D-Proline is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. With a topological polar surface area (TPSA) of 49.3 Ų, D-Proline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, D-Proline has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of D-Proline?
The CAS number of D-Proline is 344-25-2.
What is the molecular formula of D-Proline?
The molecular formula of D-Proline is C5H9NO2.
What is the molecular weight of D-Proline?
The molecular weight of D-Proline is 115.06333 g/mol.
What are the applications of D-Proline?
D-Proline is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies D-Proline (CAS 344-25-2) with custom...
Where can I buy D-Proline?
You can request a quote for D-Proline directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for D-Proline?
Yes, CoreyChem provides custom synthesis services for D-Proline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.