Benzene, 1-(chloromethyl)-2-fluoro-
TL;DR: Benzene, 1-(chloromethyl)-2-fluoro- (CAS 345-35-7) is a chemical compound with molecular formula C7H6ClF and molecular weight 144.0142 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-(chloromethyl)-2-fluorobenzene
Also Known As: 2-Fluorobenzyl chloride, 1-(Chloromethyl)-2-fluorobenzene, O-FLUOROBENZYL CHLORIDE, alpha-Chloro-o-fluorotoluene, 2-fluorobenzylchloride
Application Areas
Top 5 of 12 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C7H6ClF |
| Molecular Weight | 144.0142 g/mol |
| XLogP | 2.6 |
| Topological Polar Surface Area (TPSA) | 0.0 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 1 |
| Exact Mass | 144.0142 Da |
| Heavy Atoms | 9 |
| Complexity | 85.0 |
| SMILES | C1=CC=C(C(=C1)CCl)F |
| InChIKey | MOBRMRJUKNQBMY-UHFFFAOYSA-N |
Product Description
Applications: Benzene, 1-(chloromethyl)-2-fluoro- is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Benzene, 1-(chloromethyl)-2-fluoro- (CAS 345-35-7) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
A heterocyclic building block supplied by CoreyChem, Benzene, 1-(chloromethyl)-2-fluoro- (CAS 345-35-7) has the molecular formula C7H6ClF and a molecular weight of 144.01 g/mol. It is also known as 2-Fluorobenzyl chloride and 1-(Chloromethyl)-2-fluorobenzene.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Benzene, 1-(chloromethyl)-2-fluoro-
Property Insights of Benzene, 1-(chloromethyl)-2-fluoro-
The XLogP value of 2.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Benzene, 1-(chloromethyl)-2-fluoro-. With a topological polar surface area (TPSA) of 0.0 Ų, Benzene, 1-(chloromethyl)-2-fluoro- exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Benzene, 1-(chloromethyl)-2-fluoro- has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Benzene, 1-(chloromethyl)-2-fluoro-?
The CAS number of Benzene, 1-(chloromethyl)-2-fluoro- is 345-35-7.
What is the molecular formula of Benzene, 1-(chloromethyl)-2-fluoro-?
The molecular formula of Benzene, 1-(chloromethyl)-2-fluoro- is C7H6ClF.
What is the molecular weight of Benzene, 1-(chloromethyl)-2-fluoro-?
The molecular weight of Benzene, 1-(chloromethyl)-2-fluoro- is 144.0142 g/mol.
What are the applications of Benzene, 1-(chloromethyl)-2-fluoro-?
Benzene, 1-(chloromethyl)-2-fluoro- is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Benzene,...
Where can I buy Benzene, 1-(chloromethyl)-2-fluoro-?
You can request a quote for Benzene, 1-(chloromethyl)-2-fluoro- directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Benzene, 1-(chloromethyl)-2-fluoro-?
Yes, CoreyChem provides custom synthesis services for Benzene, 1-(chloromethyl)-2-fluoro- and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.