1-Chloro-2-fluorobenzene
TL;DR: 1-Chloro-2-fluorobenzene (CAS 348-51-6) is a chemical compound with molecular formula C6H4ClF and molecular weight 129.99855 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-chloro-2-fluorobenzene
Also Known As: 1-CHLORO-2-FLUOROBENZENE, 2-Chlorofluorobenzene, o-Chlorofluorobenzene, o-Fluorochlorobenzene, 1-Fluoro-2-chlorobenzene
Application Areas
Top 5 of 15 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C6H4ClF |
| Molecular Weight | 129.99855 g/mol |
| XLogP | 2.7 |
| Topological Polar Surface Area (TPSA) | 0.0 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 0 |
| Exact Mass | 129.99855 Da |
| Heavy Atoms | 8 |
| Complexity | 74.0 |
| Vapor Pressure | 8.19 [mmHg] |
| SMILES | C1=CC=C(C(=C1)F)Cl |
| InChIKey | ZCJAYDKWZAWMPR-UHFFFAOYSA-N |
Product Description
Applications: 1-Chloro-2-fluorobenzene is used in complex organic molecule assembly across discovery and process chemistry, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
1-Chloro-2-fluorobenzene (CAS 348-51-6) is a organic building block with the molecular formula C6H4ClF and a molecular weight of 130 g/mol. Synonyms include 1-CHLORO-2-FLUOROBENZENE and 2-Chlorofluorobenzene.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of 1-Chloro-2-fluorobenzene
Property Insights of 1-Chloro-2-fluorobenzene
The XLogP value of 2.7 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1-Chloro-2-fluorobenzene. With a topological polar surface area (TPSA) of 0.0 Ų, 1-Chloro-2-fluorobenzene exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-Chloro-2-fluorobenzene has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 1-Chloro-2-fluorobenzene?
The CAS number of 1-Chloro-2-fluorobenzene is 348-51-6.
What is the molecular formula of 1-Chloro-2-fluorobenzene?
The molecular formula of 1-Chloro-2-fluorobenzene is C6H4ClF.
What is the molecular weight of 1-Chloro-2-fluorobenzene?
The molecular weight of 1-Chloro-2-fluorobenzene is 129.99855 g/mol.
What are the applications of 1-Chloro-2-fluorobenzene?
1-Chloro-2-fluorobenzene is used in complex organic molecule assembly across discovery and process chemistry, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as...
Where can I buy 1-Chloro-2-fluorobenzene?
You can request a quote for 1-Chloro-2-fluorobenzene directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 1-Chloro-2-fluorobenzene?
Yes, CoreyChem provides custom synthesis services for 1-Chloro-2-fluorobenzene and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.