1-Fluoro-2-iodobenzene
TL;DR: 1-Fluoro-2-iodobenzene (CAS 348-52-7) is a chemical compound with molecular formula C6H4FI and molecular weight 221.93417 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-fluoro-2-iodobenzene
Also Known As: 1-Fluoro-2-iodobenzene, 2-Fluoroiodobenzene, o-Fluoroiodobenzene, o-Iodofluorobenzene, 2-iodofluorobenzene
Application Areas
Top 5 of 11 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C6H4FI |
| Molecular Weight | 221.93417 g/mol |
| XLogP | 3.1 |
| Topological Polar Surface Area (TPSA) | 0.0 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 0 |
| Exact Mass | 221.93417 Da |
| Heavy Atoms | 8 |
| Complexity | 74.0 |
| SMILES | C1=CC=C(C(=C1)F)I |
| InChIKey | TYHUGKGZNOULKD-UHFFFAOYSA-N |
Product Description
Applications: 1-Fluoro-2-iodobenzene is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies 1-Fluoro-2-iodobenzene (CAS 348-52-7) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
1-Fluoro-2-iodobenzene (CAS 348-52-7) is a heterocyclic building block with the molecular formula C6H4FI and a molecular weight of 221.93 g/mol. It is also known as 1-Fluoro-2-iodobenzene and 2-Fluoroiodobenzene.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of 1-Fluoro-2-iodobenzene
Property Insights of 1-Fluoro-2-iodobenzene
The XLogP value of 3.1 indicates that 1-Fluoro-2-iodobenzene is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 0.0 Ų, 1-Fluoro-2-iodobenzene exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-Fluoro-2-iodobenzene has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 1-Fluoro-2-iodobenzene?
The CAS number of 1-Fluoro-2-iodobenzene is 348-52-7.
What is the molecular formula of 1-Fluoro-2-iodobenzene?
The molecular formula of 1-Fluoro-2-iodobenzene is C6H4FI.
What is the molecular weight of 1-Fluoro-2-iodobenzene?
The molecular weight of 1-Fluoro-2-iodobenzene is 221.93417 g/mol.
What are the applications of 1-Fluoro-2-iodobenzene?
1-Fluoro-2-iodobenzene is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies 1-Fluoro-2-iodobenzene (CAS...
Where can I buy 1-Fluoro-2-iodobenzene?
You can request a quote for 1-Fluoro-2-iodobenzene directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 1-Fluoro-2-iodobenzene?
Yes, CoreyChem provides custom synthesis services for 1-Fluoro-2-iodobenzene and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.