4-Fluoroiodobenzene
TL;DR: 4-Fluoroiodobenzene (CAS 352-34-1) is a chemical compound with molecular formula C6H4FI and molecular weight 221.93417 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-fluoro-4-iodobenzene
Also Known As: 4-Fluoroiodobenzene, 1-FLUORO-4-IODOBENZENE, p-Fluoroiodobenzene, 4-Iodofluorobenzene, p-Iodofluorobenzene
Application Areas
Top 5 of 15 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C6H4FI |
| Molecular Weight | 221.93417 g/mol |
| XLogP | 3.4 |
| Topological Polar Surface Area (TPSA) | 0.0 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 0 |
| Exact Mass | 221.93417 Da |
| Heavy Atoms | 8 |
| Complexity | 66.0 |
| SMILES | C1=CC(=CC=C1F)I |
| InChIKey | KGNQDBQYEBMPFZ-UHFFFAOYSA-N |
Product Description
Applications: 4-Fluoroiodobenzene is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
A heterocyclic building block supplied by CoreyChem, 4-Fluoroiodobenzene (CAS 352-34-1) has the molecular formula C6H4FI and a molecular weight of 221.93 g/mol. Synonyms include 4-Fluoroiodobenzene and 1-FLUORO-4-IODOBENZENE.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of 4-Fluoroiodobenzene
Property Insights of 4-Fluoroiodobenzene
The XLogP value of 3.4 indicates that 4-Fluoroiodobenzene is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 0.0 Ų, 4-Fluoroiodobenzene exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-Fluoroiodobenzene has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 4-Fluoroiodobenzene?
The CAS number of 4-Fluoroiodobenzene is 352-34-1.
What is the molecular formula of 4-Fluoroiodobenzene?
The molecular formula of 4-Fluoroiodobenzene is C6H4FI.
What is the molecular weight of 4-Fluoroiodobenzene?
The molecular weight of 4-Fluoroiodobenzene is 221.93417 g/mol.
What are the applications of 4-Fluoroiodobenzene?
4-Fluoroiodobenzene is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy 4-Fluoroiodobenzene?
You can request a quote for 4-Fluoroiodobenzene directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 4-Fluoroiodobenzene?
Yes, CoreyChem provides custom synthesis services for 4-Fluoroiodobenzene and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.