Aniline, N-(2,2,2-trifluoroethyl)-
TL;DR: Aniline, N-(2,2,2-trifluoroethyl)- (CAS 351-61-1) is a chemical compound with molecular formula C8H8F3N and molecular weight 175.06088 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N-(2,2,2-trifluoroethyl)aniline
Also Known As: N-(2,2,2-Trifluoroethyl)aniline, N-(2,2,2-Trifluoroethyl)benzenamine, ANILINE, N-(2,2,2-TRIFLUOROETHYL)-, phenyl(2,2,2-trifluoroethyl)amine, N-(2,2,2-trifluoroethyl)-aniline
Application Areas
Top 5 of 9 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C8H8F3N |
| Molecular Weight | 175.06088 g/mol |
| XLogP | 2.9 |
| Topological Polar Surface Area (TPSA) | 12.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 175.06088 Da |
| Heavy Atoms | 12 |
| Complexity | 127.0 |
| SMILES | C1=CC=C(C=C1)NCC(F)(F)F |
| InChIKey | IHCPNFMGAKAAKN-UHFFFAOYSA-N |
Product Description
Applications: Aniline, N-(2,2,2-trifluoroethyl)- is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Aniline, N-(2,2,2-trifluoroethyl)- (CAS 351-61-1) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
Aniline, N-(2,2,2-trifluoroethyl)- (CAS 351-61-1) is a pharmaceutical intermediate with the molecular formula C8H8F3N and a molecular weight of 175.06 g/mol. It is also known as N-(2,2,2-Trifluoroethyl)aniline and N-(2,2,2-Trifluoroethyl)benzenamine.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Aniline, N-(2,2,2-trifluoroethyl)-
Property Insights of Aniline, N-(2,2,2-trifluoroethyl)-
The XLogP value of 2.9 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Aniline, N-(2,2,2-trifluoroethyl)-. With a topological polar surface area (TPSA) of 12.0 Ų, Aniline, N-(2,2,2-trifluoroethyl)- exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Aniline, N-(2,2,2-trifluoroethyl)- has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Aniline, N-(2,2,2-trifluoroethyl)-?
The CAS number of Aniline, N-(2,2,2-trifluoroethyl)- is 351-61-1.
What is the molecular formula of Aniline, N-(2,2,2-trifluoroethyl)-?
The molecular formula of Aniline, N-(2,2,2-trifluoroethyl)- is C8H8F3N.
What is the molecular weight of Aniline, N-(2,2,2-trifluoroethyl)-?
The molecular weight of Aniline, N-(2,2,2-trifluoroethyl)- is 175.06088 g/mol.
What are the applications of Aniline, N-(2,2,2-trifluoroethyl)-?
Aniline, N-(2,2,2-trifluoroethyl)- is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Aniline,...
Where can I buy Aniline, N-(2,2,2-trifluoroethyl)-?
You can request a quote for Aniline, N-(2,2,2-trifluoroethyl)- directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Aniline, N-(2,2,2-trifluoroethyl)-?
Yes, CoreyChem provides custom synthesis services for Aniline, N-(2,2,2-trifluoroethyl)- and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.