4-Fluorobenzyl chloride
TL;DR: 4-Fluorobenzyl chloride (CAS 352-11-4) is a chemical compound with molecular formula C7H6ClF and molecular weight 144.0142 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-(chloromethyl)-4-fluorobenzene
Also Known As: 4-Fluorobenzyl chloride, 1-(Chloromethyl)-4-fluorobenzene, P-FLUOROBENZYL CHLORIDE, alpha-Chloro-p-fluorotoluene, 4-fluorobenzylchloride
Application Areas
Top 5 of 14 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C7H6ClF |
| Molecular Weight | 144.0142 g/mol |
| XLogP | 2.6 |
| Topological Polar Surface Area (TPSA) | 0.0 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 1 |
| Exact Mass | 144.0142 Da |
| Heavy Atoms | 9 |
| Complexity | 77.0 |
| Vapor Pressure | 0.99 [mmHg] |
| SMILES | C1=CC(=CC=C1CCl)F |
| InChIKey | IZXWCDITFDNEBY-UHFFFAOYSA-N |
Product Description
Applications: 4-Fluorobenzyl chloride is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies 4-Fluorobenzyl chloride (CAS 352-11-4) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
4-Fluorobenzyl chloride (CAS 352-11-4) is a heterocyclic building block with the molecular formula C7H6ClF and a molecular weight of 144.01 g/mol. It is also known as 4-Fluorobenzyl chloride and 1-(Chloromethyl)-4-fluorobenzene.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of 4-Fluorobenzyl chloride
Property Insights of 4-Fluorobenzyl chloride
The XLogP value of 2.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 4-Fluorobenzyl chloride. With a topological polar surface area (TPSA) of 0.0 Ų, 4-Fluorobenzyl chloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-Fluorobenzyl chloride has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 4-Fluorobenzyl chloride?
The CAS number of 4-Fluorobenzyl chloride is 352-11-4.
What is the molecular formula of 4-Fluorobenzyl chloride?
The molecular formula of 4-Fluorobenzyl chloride is C7H6ClF.
What is the molecular weight of 4-Fluorobenzyl chloride?
The molecular weight of 4-Fluorobenzyl chloride is 144.0142 g/mol.
What are the applications of 4-Fluorobenzyl chloride?
4-Fluorobenzyl chloride is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies 4-Fluorobenzyl chloride (CAS...
Where can I buy 4-Fluorobenzyl chloride?
You can request a quote for 4-Fluorobenzyl chloride directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 4-Fluorobenzyl chloride?
Yes, CoreyChem provides custom synthesis services for 4-Fluorobenzyl chloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.