1,1,2-Trichloro-2-fluoroethane
TL;DR: 1,1,2-Trichloro-2-fluoroethane (CAS 359-28-4) is a chemical compound with molecular formula C2H2Cl3F and molecular weight 149.92061 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1,1,2-trichloro-2-fluoroethane
Also Known As: 1-Fluoro-1,2,2-trichloroethane, 1,1,2-TRICHLORO-2-FLUOROETHANE, R 131 (refrigerant), 2-Fluoro-1,1,2-trichloroethane, Trichlorofluoroethane
Application Areas
Top 5 of 21 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C2H2Cl3F |
| Molecular Weight | 149.92061 g/mol |
| XLogP | 2.7 |
| Topological Polar Surface Area (TPSA) | 0.0 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 1 |
| Exact Mass | 149.92061 Da |
| Heavy Atoms | 6 |
| Complexity | 37.0 |
| SMILES | C(C(Cl)Cl)(F)Cl |
| InChIKey | ORMSTDJYMPIZAO-UHFFFAOYSA-N |
Product Description
Applications: 1,1,2-Trichloro-2-fluoroethane is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies 1,1,2-Trichloro-2-fluoroethane (CAS 359-28-4) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
1,1,2-Trichloro-2-fluoroethane (CAS 359-28-4) is a pharmaceutical intermediate with the molecular formula C2H2Cl3F and a molecular weight of 149.92 g/mol. It is also known as 1-Fluoro-1,2,2-trichloroethane and 1,1,2-TRICHLORO-2-FLUOROETHANE.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of 1,1,2-Trichloro-2-fluoroethane
Property Insights of 1,1,2-Trichloro-2-fluoroethane
The XLogP value of 2.7 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1,1,2-Trichloro-2-fluoroethane. With a topological polar surface area (TPSA) of 0.0 Ų, 1,1,2-Trichloro-2-fluoroethane exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1,1,2-Trichloro-2-fluoroethane has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 1,1,2-Trichloro-2-fluoroethane?
The CAS number of 1,1,2-Trichloro-2-fluoroethane is 359-28-4.
What is the molecular formula of 1,1,2-Trichloro-2-fluoroethane?
The molecular formula of 1,1,2-Trichloro-2-fluoroethane is C2H2Cl3F.
What is the molecular weight of 1,1,2-Trichloro-2-fluoroethane?
The molecular weight of 1,1,2-Trichloro-2-fluoroethane is 149.92061 g/mol.
What are the applications of 1,1,2-Trichloro-2-fluoroethane?
1,1,2-Trichloro-2-fluoroethane is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies...
Where can I buy 1,1,2-Trichloro-2-fluoroethane?
You can request a quote for 1,1,2-Trichloro-2-fluoroethane directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 1,1,2-Trichloro-2-fluoroethane?
Yes, CoreyChem provides custom synthesis services for 1,1,2-Trichloro-2-fluoroethane and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.