Buspirone
TL;DR: Buspirone (CAS 36505-84-7) is a chemical compound with molecular formula C21H31N5O2 and molecular weight 385.24777 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
8-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]-8-azaspiro[4.5]decane-7,9-dione
Also Known As: buspirone, Buspirona, Ansial, Buspironum, Buspar
Application Areas
Top 5 of 16 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C21H31N5O2 |
| Molecular Weight | 385.24777 g/mol |
| XLogP | 2.6 |
| Topological Polar Surface Area (TPSA) | 69.6 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 6 |
| Exact Mass | 385.24777 Da |
| Heavy Atoms | 28 |
| Complexity | 529.0 |
| Melting Point | 201.5-202.5 |
| Solubility | 5.88e-01 g/L |
| SMILES | C1CCC2(C1)CC(=O)N(C(=O)C2)CCCCN3CCN(CC3)C4=NC=CC=N4 |
| InChIKey | QWCRAEMEVRGPNT-UHFFFAOYSA-N |
Product Description
Applications: Buspirone is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Buspirone (CAS 36505-84-7) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
Buspirone is a pharmaceutical intermediate identified by CAS number 36505-84-7 and the molecular formula C21H31N5O2 and a molecular weight of 385.25 g/mol. Physically, the compound has a solubility: 5.88e-01 g/L. It is also known as buspirone and Buspirona.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Buspirone
Property Insights of Buspirone
The XLogP value of 2.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Buspirone. The TPSA of 69.6 Ų falls within the moderate polarity range, balancing permeability and solubility for Buspirone. Following Lipinski's Rule of Five, Buspirone has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Buspirone?
The CAS number of Buspirone is 36505-84-7.
What is the molecular formula of Buspirone?
The molecular formula of Buspirone is C21H31N5O2.
What is the molecular weight of Buspirone?
The molecular weight of Buspirone is 385.24777 g/mol.
What are the applications of Buspirone?
Buspirone is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Buspirone (CAS 36505-84-7) with custom...
Where can I buy Buspirone?
You can request a quote for Buspirone directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Buspirone?
Yes, CoreyChem provides custom synthesis services for Buspirone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.