1,3-Difluorobenzene
TL;DR: 1,3-Difluorobenzene (CAS 372-18-9) is a chemical compound with molecular formula C6H4F2 and molecular weight 114.02811 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1,3-difluorobenzene
Also Known As: 1,3-DIFLUOROBENZENE, m-Difluorobenzene, Benzene, 1,3-difluoro-, Benzene, m-difluoro-, 2,4-difluorobenzene
Application Areas
Top 5 of 15 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C6H4F2 |
| Molecular Weight | 114.02811 g/mol |
| XLogP | 2.4 |
| Topological Polar Surface Area (TPSA) | 0.0 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 0 |
| Exact Mass | 114.02811 Da |
| Heavy Atoms | 8 |
| Complexity | 64.0 |
| SMILES | C1=CC(=CC(=C1)F)F |
| InChIKey | UEMGWPRHOOEKTA-UHFFFAOYSA-N |
Product Description
Applications: 1,3-Difluorobenzene is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies 1,3-Difluorobenzene (CAS 372-18-9) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
1,3-Difluorobenzene is a heterocyclic building block identified by CAS number 372-18-9 and the molecular formula C6H4F2 and a molecular weight of 114.03 g/mol. It is also known as 1,3-DIFLUOROBENZENE and m-Difluorobenzene.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of 1,3-Difluorobenzene
Property Insights of 1,3-Difluorobenzene
The XLogP value of 2.4 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1,3-Difluorobenzene. With a topological polar surface area (TPSA) of 0.0 Ų, 1,3-Difluorobenzene exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1,3-Difluorobenzene has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 1,3-Difluorobenzene?
The CAS number of 1,3-Difluorobenzene is 372-18-9.
What is the molecular formula of 1,3-Difluorobenzene?
The molecular formula of 1,3-Difluorobenzene is C6H4F2.
What is the molecular weight of 1,3-Difluorobenzene?
The molecular weight of 1,3-Difluorobenzene is 114.02811 g/mol.
What are the applications of 1,3-Difluorobenzene?
1,3-Difluorobenzene is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies 1,3-Difluorobenzene (CAS 372-18-9)...
Where can I buy 1,3-Difluorobenzene?
You can request a quote for 1,3-Difluorobenzene directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 1,3-Difluorobenzene?
Yes, CoreyChem provides custom synthesis services for 1,3-Difluorobenzene and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.