Nalidixic Acid
TL;DR: Nalidixic Acid (CAS 389-08-2) is a chemical compound with molecular formula C12H12N2O3 and molecular weight 232.0848 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid
Also Known As: nalidixic acid, Nalidixin, Nalidixate, Nevigramon, NegGram
Application Areas
Top 5 of 20 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C12H12N2O3 |
| Molecular Weight | 232.0848 g/mol |
| XLogP | 1.4 |
| Topological Polar Surface Area (TPSA) | 70.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 232.0848 Da |
| Heavy Atoms | 17 |
| Complexity | 378.0 |
| Melting Point | 444 to 446 °F (NTP, 1992) |
| Solubility | less than 1 mg/mL at 70 °F (NTP, 1992) |
| SMILES | CCN1C=C(C(=O)C2=C1N=C(C=C2)C)C(=O)O |
| InChIKey | MHWLWQUZZRMNGJ-UHFFFAOYSA-N |
Product Description
Applications: Nalidixic Acid is used in pharmaceutical synthesis routes and API production, as well as biotechnology workflows and life-science research. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Nalidixic Acid (CAS 389-08-2) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
Nalidixic Acid is a pharmaceutical intermediate identified by CAS number 389-08-2 and the molecular formula C12H12N2O3 and a molecular weight of 232.08 g/mol. Physically, the compound has a solubility: less than 1 mg/mL at 70 °F (NTP, 1992). It is also known as nalidixic acid and Nalidixin.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Nalidixic Acid
Property Insights of Nalidixic Acid
The XLogP value of 1.4 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Nalidixic Acid. The TPSA of 70.5 Ų falls within the moderate polarity range, balancing permeability and solubility for Nalidixic Acid. Following Lipinski's Rule of Five, Nalidixic Acid has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Nalidixic Acid?
The CAS number of Nalidixic Acid is 389-08-2.
What is the molecular formula of Nalidixic Acid?
The molecular formula of Nalidixic Acid is C12H12N2O3.
What is the molecular weight of Nalidixic Acid?
The molecular weight of Nalidixic Acid is 232.0848 g/mol.
What are the applications of Nalidixic Acid?
Nalidixic Acid is used in pharmaceutical synthesis routes and API production, as well as biotechnology workflows and life-science research. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Nalidixic Acid (CAS 389-08-2) with custom synthesis available...
Where can I buy Nalidixic Acid?
You can request a quote for Nalidixic Acid directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Nalidixic Acid?
Yes, CoreyChem provides custom synthesis services for Nalidixic Acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.