Nitrendipine
TL;DR: Nitrendipine (CAS 39562-70-4) is a chemical compound with molecular formula C18H20N2O6 and molecular weight 360.13214 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
5-O-ethyl 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Also Known As: nitrendipine, Bayotensin, Baypress, Nidrel, Deiten
Application Areas
Top 5 of 15 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C18H20N2O6 |
| Molecular Weight | 360.13214 g/mol |
| XLogP | 2.9 |
| Topological Polar Surface Area (TPSA) | 110.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 6 |
| Exact Mass | 360.13214 Da |
| Heavy Atoms | 26 |
| Complexity | 661.0 |
| Melting Point | 156-160 °C |
| Solubility | Insoluble |
| SMILES | CCOC(=O)C1=C(NC(=C(C1C2=CC(=CC=C2)[N+](=O)[O-])C(=O)OC)C)C |
| InChIKey | PVHUJELLJLJGLN-UHFFFAOYSA-N |
Product Description
Applications: Nitrendipine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Nitrendipine is a pharmaceutical intermediate identified by CAS number 39562-70-4 and the molecular formula C18H20N2O6 and a molecular weight of 360.13 g/mol. Physically, the compound has a solubility: Insoluble. Synonyms include nitrendipine and Bayotensin.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Nitrendipine
Property Insights of Nitrendipine
The XLogP value of 2.9 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Nitrendipine. The TPSA of 110.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Nitrendipine. Following Lipinski's Rule of Five, Nitrendipine has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Nitrendipine?
The CAS number of Nitrendipine is 39562-70-4.
What is the molecular formula of Nitrendipine?
The molecular formula of Nitrendipine is C18H20N2O6.
What is the molecular weight of Nitrendipine?
The molecular weight of Nitrendipine is 360.13214 g/mol.
What are the applications of Nitrendipine?
Nitrendipine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Nitrendipine?
You can request a quote for Nitrendipine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Nitrendipine?
Yes, CoreyChem provides custom synthesis services for Nitrendipine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.