2,6-Bis(trifluoromethyl)-1H-benzimidazole
TL;DR: 2,6-Bis(trifluoromethyl)-1H-benzimidazole (CAS 399-69-9) is a chemical compound with molecular formula C9H4F6N2 and molecular weight 254.02786 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2,6-bis(trifluoromethyl)-1H-benzimidazole
Also Known As: 2,6-bis(trifluoromethyl)-1H-benzimidazole, BENZIMIDAZOLE, 2,5-BIS(TRIFLUOROMETHYL)-, 2,5-Bis(trifluoromethyl)-1H-benzo[d]imidazole, 2,5-Bis(trifluoromethyl)benzimidazole, 2,5-ditrifluoromethylbenzimidazole
Application Areas
Top 5 of 3 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C9H4F6N2 |
| Molecular Weight | 254.02786 g/mol |
| XLogP | 3.3 |
| Topological Polar Surface Area (TPSA) | 28.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 0 |
| Exact Mass | 254.02786 Da |
| Heavy Atoms | 17 |
| Complexity | 286.0 |
| SMILES | C1=CC2=C(C=C1C(F)(F)F)NC(=N2)C(F)(F)F |
| InChIKey | BKFXAUQYNCJXIZ-UHFFFAOYSA-N |
Product Description
Applications: 2,6-Bis(trifluoromethyl)-1H-benzimidazole is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as agrochemical development, including crop protection agent synthesis. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies 2,6-Bis(trifluoromethyl)-1H-benzimidazole (CAS 399-69-9) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
A heterocyclic building block supplied by CoreyChem, 2,6-Bis(trifluoromethyl)-1H-benzimidazole (CAS 399-69-9) has the molecular formula C9H4F6N2 and a molecular weight of 254.03 g/mol. It is also known as 2,6-bis(trifluoromethyl)-1H-benzimidazole and BENZIMIDAZOLE, 2,5-BIS(TRIFLUOROMETHYL)-.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of 2,6-Bis(trifluoromethyl)-1H-benzimidazole
Property Insights of 2,6-Bis(trifluoromethyl)-1H-benzimidazole
The XLogP value of 3.3 indicates that 2,6-Bis(trifluoromethyl)-1H-benzimidazole is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 28.7 Ų, 2,6-Bis(trifluoromethyl)-1H-benzimidazole exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2,6-Bis(trifluoromethyl)-1H-benzimidazole has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 2,6-Bis(trifluoromethyl)-1H-benzimidazole?
The CAS number of 2,6-Bis(trifluoromethyl)-1H-benzimidazole is 399-69-9.
What is the molecular formula of 2,6-Bis(trifluoromethyl)-1H-benzimidazole?
The molecular formula of 2,6-Bis(trifluoromethyl)-1H-benzimidazole is C9H4F6N2.
What is the molecular weight of 2,6-Bis(trifluoromethyl)-1H-benzimidazole?
The molecular weight of 2,6-Bis(trifluoromethyl)-1H-benzimidazole is 254.02786 g/mol.
What are the applications of 2,6-Bis(trifluoromethyl)-1H-benzimidazole?
2,6-Bis(trifluoromethyl)-1H-benzimidazole is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as agrochemical development, including crop protection agent synthesis. It commonly serves as a versatile building block for organic synthesis. CoreyChem...
Where can I buy 2,6-Bis(trifluoromethyl)-1H-benzimidazole?
You can request a quote for 2,6-Bis(trifluoromethyl)-1H-benzimidazole directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 2,6-Bis(trifluoromethyl)-1H-benzimidazole?
Yes, CoreyChem provides custom synthesis services for 2,6-Bis(trifluoromethyl)-1H-benzimidazole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.