2-(1,2,2,2-Tetrafluoroethyl)-1H-benzimidazole
TL;DR: 2-(1,2,2,2-Tetrafluoroethyl)-1H-benzimidazole (CAS 41185-74-4) is a chemical compound with molecular formula C9H6F4N2 and molecular weight 218.0467 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-(1,2,2,2-tetrafluoroethyl)-1H-benzimidazole
Also Known As: 2-FETB, 2-TFEB, 2-(1,2,2,2-Tetrafluoroethyl)-1H-benzimidazole, tetrafluoroethylbenz imidazole, 2-(1,2,2,2-tetrafluoroethyl)benzimidazole
Application Areas
Top 5 of 1 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C9H6F4N2 |
| Molecular Weight | 218.0467 g/mol |
| XLogP | 3.1 |
| Topological Polar Surface Area (TPSA) | 28.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 1 |
| Exact Mass | 218.0467 Da |
| Heavy Atoms | 15 |
| Complexity | 231.0 |
| Solubility | >32.7 [ug/mL] (The mean of the results at pH 7.4) |
| SMILES | C1=CC=C2C(=C1)NC(=N2)C(C(F)(F)F)F |
| InChIKey | QOXFGGCVUDFHNX-UHFFFAOYSA-N |
Product Description
Applications: 2-(1,2,2,2-Tetrafluoroethyl)-1H-benzimidazole is used in heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies 2-(1,2,2,2-Tetrafluoroethyl)-1H-benzimidazole (CAS 41185-74-4) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
A heterocyclic building block supplied by CoreyChem, 2-(1,2,2,2-Tetrafluoroethyl)-1H-benzimidazole (CAS 41185-74-4) has the molecular formula C9H6F4N2 and a molecular weight of 218.05 g/mol. Reported properties include a solubility: >32.7 [ug/mL] (The mean of the results at pH 7.4). It is also known as 2-FETB and 2-TFEB.
CoreyChem provides it with COA documentation, and custom synthesis from milligram to multi-kilogram scales is available on request. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of 2-(1,2,2,2-Tetrafluoroethyl)-1H-benzimidazole
Property Insights of 2-(1,2,2,2-Tetrafluoroethyl)-1H-benzimidazole
The XLogP value of 3.1 indicates that 2-(1,2,2,2-Tetrafluoroethyl)-1H-benzimidazole is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 28.7 Ų, 2-(1,2,2,2-Tetrafluoroethyl)-1H-benzimidazole exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-(1,2,2,2-Tetrafluoroethyl)-1H-benzimidazole has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 2-(1,2,2,2-Tetrafluoroethyl)-1H-benzimidazole?
The CAS number of 2-(1,2,2,2-Tetrafluoroethyl)-1H-benzimidazole is 41185-74-4.
What is the molecular formula of 2-(1,2,2,2-Tetrafluoroethyl)-1H-benzimidazole?
The molecular formula of 2-(1,2,2,2-Tetrafluoroethyl)-1H-benzimidazole is C9H6F4N2.
What is the molecular weight of 2-(1,2,2,2-Tetrafluoroethyl)-1H-benzimidazole?
The molecular weight of 2-(1,2,2,2-Tetrafluoroethyl)-1H-benzimidazole is 218.0467 g/mol.
What are the applications of 2-(1,2,2,2-Tetrafluoroethyl)-1H-benzimidazole?
2-(1,2,2,2-Tetrafluoroethyl)-1H-benzimidazole is used in heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies 2-(1,2,2,2-Tetrafluoroethyl)-1H-benzimidazole (CAS 41185-74-4) with...
Where can I buy 2-(1,2,2,2-Tetrafluoroethyl)-1H-benzimidazole?
You can request a quote for 2-(1,2,2,2-Tetrafluoroethyl)-1H-benzimidazole directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 2-(1,2,2,2-Tetrafluoroethyl)-1H-benzimidazole?
Yes, CoreyChem provides custom synthesis services for 2-(1,2,2,2-Tetrafluoroethyl)-1H-benzimidazole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.