1,1,1-Trifluoroethane
TL;DR: 1,1,1-Trifluoroethane (CAS 420-46-2) is a chemical compound with molecular formula C2H3F3 and molecular weight 84.018684 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1,1,1-trifluoroethane
Also Known As: 1,1,1-TRIFLUOROETHANE, Methylfluoroform, Trifluoroethane, 1,1,1-Trifluoroform, Fluorocarbon FC143a
Application Areas
Top 5 of 22 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C2H3F3 |
| Molecular Weight | 84.018684 g/mol |
| XLogP | 1.7 |
| Topological Polar Surface Area (TPSA) | 0.0 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 0 |
| Exact Mass | 84.018684 Da |
| Heavy Atoms | 5 |
| Complexity | 26.0 |
| Melting Point | -111.8 °C |
| Boiling Point | -47.20 °C |
| Density | Density: 1.176 g/mL at -50 °C |
| Vapor Pressure | 1262 kPa at 298.165 deg K (9465 mm Hg at 25 °C) |
| Refractive Index | Liquid refractive index: 1.22 at 25 °C |
| Solubility | Soluble in ethyl ether, chloroform |
| SMILES | CC(F)(F)F |
| InChIKey | UJPMYEOUBPIPHQ-UHFFFAOYSA-N |
Product Description
Applications: 1,1,1-Trifluoroethane is used in pharmaceutical synthesis routes and API production, as well as polymer chemistry and functional materials synthesis. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
1,1,1-Trifluoroethane is a pharmaceutical intermediate identified by CAS number 420-46-2 and the molecular formula C2H3F3 and a molecular weight of 84.02 g/mol. Physically, the compound has a density of Density: 1.176 g/mL at -50 °C g/cm³, a solubility: Soluble in ethyl ether, chloroform. Synonyms include 1,1,1-TRIFLUOROETHANE and Methylfluoroform.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of 1,1,1-Trifluoroethane
Property Insights of 1,1,1-Trifluoroethane
The XLogP value of 1.7 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1,1,1-Trifluoroethane. With a topological polar surface area (TPSA) of 0.0 Ų, 1,1,1-Trifluoroethane exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1,1,1-Trifluoroethane has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 1,1,1-Trifluoroethane?
The CAS number of 1,1,1-Trifluoroethane is 420-46-2.
What is the molecular formula of 1,1,1-Trifluoroethane?
The molecular formula of 1,1,1-Trifluoroethane is C2H3F3.
What is the molecular weight of 1,1,1-Trifluoroethane?
The molecular weight of 1,1,1-Trifluoroethane is 84.018684 g/mol.
What are the applications of 1,1,1-Trifluoroethane?
1,1,1-Trifluoroethane is used in pharmaceutical synthesis routes and API production, as well as polymer chemistry and functional materials synthesis. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project...
Where can I buy 1,1,1-Trifluoroethane?
You can request a quote for 1,1,1-Trifluoroethane directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 1,1,1-Trifluoroethane?
Yes, CoreyChem provides custom synthesis services for 1,1,1-Trifluoroethane and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.