Midodrine
TL;DR: Midodrine (CAS 42794-76-3) is a chemical compound with molecular formula C12H18N2O4 and molecular weight 254.12666 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]acetamide
Also Known As: midodrine, Midodrin, Midodrina, Midodrinum, Midodrine HCL
Application Areas
Top 5 of 11 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C12H18N2O4 |
| Molecular Weight | 254.12666 g/mol |
| XLogP | -0.6 |
| Topological Polar Surface Area (TPSA) | 93.8 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 254.12666 Da |
| Heavy Atoms | 18 |
| Complexity | 262.0 |
| Melting Point | 200 |
| Solubility | Soluble |
| SMILES | COC1=CC(=C(C=C1)OC)C(CNC(=O)CN)O |
| InChIKey | PTKSEFOSCHHMPD-UHFFFAOYSA-N |
Product Description
Applications: Midodrine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Midodrine (CAS 42794-76-3) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
Midodrine is a pharmaceutical intermediate identified by CAS number 42794-76-3 and the molecular formula C12H18N2O4 and a molecular weight of 254.13 g/mol. Physically, the compound has a solubility: Soluble. It is also known as midodrine and Midodrin.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Midodrine
Property Insights of Midodrine
The XLogP value of -0.6 indicates that Midodrine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 93.8 Ų falls within the moderate polarity range, balancing permeability and solubility for Midodrine. Following Lipinski's Rule of Five, Midodrine has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Midodrine?
The CAS number of Midodrine is 42794-76-3.
What is the molecular formula of Midodrine?
The molecular formula of Midodrine is C12H18N2O4.
What is the molecular weight of Midodrine?
The molecular weight of Midodrine is 254.12666 g/mol.
What are the applications of Midodrine?
Midodrine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Midodrine (CAS 42794-76-3) with custom...
Where can I buy Midodrine?
You can request a quote for Midodrine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Midodrine?
Yes, CoreyChem provides custom synthesis services for Midodrine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.