Profadol
TL;DR: Profadol (CAS 428-37-5) is a chemical compound with molecular formula C14H21NO and molecular weight 219.16231 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
3-(1-methyl-3-propylpyrrolidin-3-yl)phenol
Also Known As: PROFADOL, Profadolum, Dl-profadol, Profadol, (+)-, Profadol [INN:BAN]
Application Areas
Top 5 of 9 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C14H21NO |
| Molecular Weight | 219.16231 g/mol |
| XLogP | 3.2 |
| Topological Polar Surface Area (TPSA) | 23.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 3 |
| Exact Mass | 219.16231 Da |
| Heavy Atoms | 16 |
| Complexity | 231.0 |
| SMILES | CCCC1(CCN(C1)C)C2=CC(=CC=C2)O |
| InChIKey | VFUGCQKESINERB-UHFFFAOYSA-N |
Product Description
Applications: Profadol is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Profadol (CAS 428-37-5) is a pharmaceutical intermediate with the molecular formula C14H21NO and a molecular weight of 219.16 g/mol. Synonyms include PROFADOL and Profadolum.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Profadol
Property Insights of Profadol
The XLogP value of 3.2 indicates that Profadol is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 23.5 Ų, Profadol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Profadol has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Profadol?
The CAS number of Profadol is 428-37-5.
What is the molecular formula of Profadol?
The molecular formula of Profadol is C14H21NO.
What is the molecular weight of Profadol?
The molecular weight of Profadol is 219.16231 g/mol.
What are the applications of Profadol?
Profadol is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Profadol?
You can request a quote for Profadol directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Profadol?
Yes, CoreyChem provides custom synthesis services for Profadol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.