Nabumetone
TL;DR: Nabumetone (CAS 42924-53-8) is a chemical compound with molecular formula C15H16O2 and molecular weight 228.11504 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
4-(6-methoxynaphthalen-2-yl)butan-2-one
Also Known As: nabumetone, Relafen, Arthaxan, Nabumetona, Relifen
Application Areas
Top 5 of 17 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C15H16O2 |
| Molecular Weight | 228.11504 g/mol |
| XLogP | 3.1 |
| Topological Polar Surface Area (TPSA) | 26.3 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 4 |
| Exact Mass | 228.11504 Da |
| Heavy Atoms | 17 |
| Complexity | 262.0 |
| Melting Point | 78-82 |
| Solubility | Practically insoluble |
| SMILES | CC(=O)CCC1=CC2=C(C=C1)C=C(C=C2)OC |
| InChIKey | BLXXJMDCKKHMKV-UHFFFAOYSA-N |
Product Description
Applications: Nabumetone is used in pharmaceutical synthesis routes and API production, as well as biotechnology workflows and life-science research. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Nabumetone (CAS 42924-53-8) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
Nabumetone (CAS 42924-53-8) is a pharmaceutical intermediate with the molecular formula C15H16O2 and a molecular weight of 228.12 g/mol. Key physical properties include a solubility: Practically insoluble. It is also known as nabumetone and Relafen.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Nabumetone
Property Insights of Nabumetone
The XLogP value of 3.1 indicates that Nabumetone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 26.3 Ų, Nabumetone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Nabumetone has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Nabumetone?
The CAS number of Nabumetone is 42924-53-8.
What is the molecular formula of Nabumetone?
The molecular formula of Nabumetone is C15H16O2.
What is the molecular weight of Nabumetone?
The molecular weight of Nabumetone is 228.11504 g/mol.
What are the applications of Nabumetone?
Nabumetone is used in pharmaceutical synthesis routes and API production, as well as biotechnology workflows and life-science research. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Nabumetone (CAS 42924-53-8) with custom synthesis available from...
Where can I buy Nabumetone?
You can request a quote for Nabumetone directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Nabumetone?
Yes, CoreyChem provides custom synthesis services for Nabumetone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.