2-Chloro-6-fluorotoluene
TL;DR: 2-Chloro-6-fluorotoluene (CAS 443-83-4) is a chemical compound with molecular formula C7H6ClF and molecular weight 144.0142 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-chloro-3-fluoro-2-methylbenzene
Also Known As: 2-Chloro-6-fluorotoluene, 1-Chloro-3-fluoro-2-methylbenzene, 6-chloro-2-fluorotoluene, 2-FLUORO-6-CHLOROTOLUENE, 2Cloro 6Fluorotoluene
Application Areas
Top 5 of 13 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C7H6ClF |
| Molecular Weight | 144.0142 g/mol |
| XLogP | 3.8 |
| Topological Polar Surface Area (TPSA) | 0.0 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 0 |
| Exact Mass | 144.0142 Da |
| Heavy Atoms | 9 |
| Complexity | 94.0 |
| SMILES | CC1=C(C=CC=C1Cl)F |
| InChIKey | FNPVYRJTBXHIPB-UHFFFAOYSA-N |
Product Description
Applications: 2-Chloro-6-fluorotoluene is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as complex organic molecule assembly across discovery and process chemistry. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
A heterocyclic building block supplied by CoreyChem, 2-Chloro-6-fluorotoluene (CAS 443-83-4) has the molecular formula C7H6ClF and a molecular weight of 144.01 g/mol. Synonyms include 2-Chloro-6-fluorotoluene and 1-Chloro-3-fluoro-2-methylbenzene.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of 2-Chloro-6-fluorotoluene
Property Insights of 2-Chloro-6-fluorotoluene
The XLogP value of 3.8 indicates that 2-Chloro-6-fluorotoluene is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 0.0 Ų, 2-Chloro-6-fluorotoluene exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-Chloro-6-fluorotoluene has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 2-Chloro-6-fluorotoluene?
The CAS number of 2-Chloro-6-fluorotoluene is 443-83-4.
What is the molecular formula of 2-Chloro-6-fluorotoluene?
The molecular formula of 2-Chloro-6-fluorotoluene is C7H6ClF.
What is the molecular weight of 2-Chloro-6-fluorotoluene?
The molecular weight of 2-Chloro-6-fluorotoluene is 144.0142 g/mol.
What are the applications of 2-Chloro-6-fluorotoluene?
2-Chloro-6-fluorotoluene is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as complex organic molecule assembly across discovery and process chemistry. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as...
Where can I buy 2-Chloro-6-fluorotoluene?
You can request a quote for 2-Chloro-6-fluorotoluene directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 2-Chloro-6-fluorotoluene?
Yes, CoreyChem provides custom synthesis services for 2-Chloro-6-fluorotoluene and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.