Jervine
TL;DR: Jervine (CAS 469-59-0) is a chemical compound with molecular formula C27H39NO3 and molecular weight 425.293 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(3S,3'R,3'aS,6'S,6aS,6bS,7'aR,9R,11aS,11bR)-3-hydroxy-3',6',10,11b-tetramethylspiro[1,2,3,4,6,6a,6b,7,8,11a-decahydrobenzo[a]fluorene-9,2'-3a,4,5,6,7,7a-hexahydro-3H-furo[3,2-b]pyridine]-11-one
Also Known As: JERVINE, Iervin, Jerwiny, 11-Ketocyclopamine, jervin
Application Areas
Top 5 of 7 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C27H39NO3 |
| Molecular Weight | 425.293 g/mol |
| XLogP | 2.9 |
| Topological Polar Surface Area (TPSA) | 58.6 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 0 |
| Exact Mass | 425.293 Da |
| Heavy Atoms | 31 |
| Complexity | 876.0 |
| Melting Point | 243.5-244.5 °C |
| Solubility | SOL IN ALCOHOL, ACETONE, CHLOROFORM |
| SMILES | C[C@H]1C[C@@H]2[C@H]([C@H]([C@]3(O2)CC[C@H]4[C@@H]5CC=C6C[C@H](CC[C@@]6([C@H]5C(=O)C4=C3C)C)O)C)NC1 |
| InChIKey | CLEXYFLHGFJONT-DNMILWOZSA-N |
Product Description
Applications: Jervine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Jervine is a pharmaceutical intermediate identified by CAS number 469-59-0 and the molecular formula C27H39NO3 and a molecular weight of 425.29 g/mol. Physically, the compound has a solubility: SOL IN ALCOHOL, ACETONE, CHLOROFORM. Synonyms include JERVINE and Iervin.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Jervine
Property Insights of Jervine
The XLogP value of 2.9 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Jervine. With a topological polar surface area (TPSA) of 58.6 Ų, Jervine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Jervine has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Jervine?
The CAS number of Jervine is 469-59-0.
What is the molecular formula of Jervine?
The molecular formula of Jervine is C27H39NO3.
What is the molecular weight of Jervine?
The molecular weight of Jervine is 425.293 g/mol.
What are the applications of Jervine?
Jervine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis...
Where can I buy Jervine?
You can request a quote for Jervine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Jervine?
Yes, CoreyChem provides custom synthesis services for Jervine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.