Propiolic Acid
TL;DR: Propiolic Acid (CAS 471-25-0) is a chemical compound with molecular formula C3H2O2 and molecular weight 70.00548 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
prop-2-ynoic acid
Also Known As: PROPIOLIC ACID, 2-Propynoic acid, Propargylic acid, Propynoic acid, prop-2-ynoic acid
Application Areas
Top 5 of 22 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C3H2O2 |
| Molecular Weight | 70.00548 g/mol |
| XLogP | 0.3 |
| Topological Polar Surface Area (TPSA) | 37.3 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 0 |
| Exact Mass | 70.00548 Da |
| Heavy Atoms | 5 |
| Complexity | 84.0 |
| Melting Point | 18 °C |
| Boiling Point | 144 °C (decomposes) |
| Density | 1.1380 g/cu cm at 20 °C |
| Flash Point | 58 °C (136 °F) - closed cup |
| Vapor Pressure | 3.5 [mmHg] |
| Refractive Index | Index of refraction: 1.4306 at 20 °C/D |
| Solubility | Very soluble in water, ether, ethanol, chloroform |
| SMILES | C#CC(=O)O |
| InChIKey | UORVCLMRJXCDCP-UHFFFAOYSA-N |
Product Description
Applications: Propiolic Acid is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Propiolic Acid (CAS 471-25-0) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
A pharmaceutical intermediate supplied by CoreyChem, Propiolic Acid (CAS 471-25-0) has the molecular formula C3H2O2 and a molecular weight of 70.01 g/mol. Reported properties include a density of 1.1380 g/cu cm at 20 °C g/cm³, a solubility: Very soluble in water, ether, ethanol, chloroform. It is also known as PROPIOLIC ACID and 2-Propynoic acid.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Propiolic Acid
Property Insights of Propiolic Acid
The XLogP value of 0.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Propiolic Acid. With a topological polar surface area (TPSA) of 37.3 Ų, Propiolic Acid exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Propiolic Acid has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Propiolic Acid?
The CAS number of Propiolic Acid is 471-25-0.
What is the molecular formula of Propiolic Acid?
The molecular formula of Propiolic Acid is C3H2O2.
What is the molecular weight of Propiolic Acid?
The molecular weight of Propiolic Acid is 70.00548 g/mol.
What are the applications of Propiolic Acid?
Propiolic Acid is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Propiolic Acid (CAS 471-25-0) with...
Where can I buy Propiolic Acid?
You can request a quote for Propiolic Acid directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Propiolic Acid?
Yes, CoreyChem provides custom synthesis services for Propiolic Acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.