Rhein
TL;DR: Rhein (CAS 478-43-3) is a chemical compound with molecular formula C15H8O6 and molecular weight 284.03207 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
大黄酸
4,5-dihydroxy-9,10-dioxoanthracene-2-carboxylic acid
Also Known As: Rhein, Monorhein, Cassic acid, Rhubarb Yellow, Rheic acid
Application Areas
Top 5 of 22 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C15H8O6 |
| Molecular Weight | 284.03207 g/mol |
| XLogP | 2.2 |
| Topological Polar Surface Area (TPSA) | 112.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 1 |
| Exact Mass | 284.03207 Da |
| Heavy Atoms | 21 |
| Complexity | 487.0 |
| Melting Point | 610 °F (NTP, 1992) |
| Boiling Point | Sublimes (NTP, 1992) |
| Solubility | less than 1 mg/mL at 63 °F (NTP, 1992) |
| SMILES | C1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=C(C=C3O)C(=O)O |
| InChIKey | FCDLCPWAQCPTKC-UHFFFAOYSA-N |
Product Description
Applications: Rhein is used in polymer chemistry and functional materials synthesis, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Rhein (CAS 478-43-3) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
Rhein is a polymer intermediate identified by CAS number 478-43-3 and the molecular formula C15H8O6 and a molecular weight of 284.03 g/mol. Physically, the compound has a solubility: less than 1 mg/mL at 63 °F (NTP, 1992). It is also known as Rhein and Monorhein.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Rhein
Property Insights of Rhein
The XLogP value of 2.2 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Rhein. The TPSA of 112.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Rhein. Following Lipinski's Rule of Five, Rhein has 3 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Rhein?
The CAS number of Rhein is 478-43-3.
What is the molecular formula of Rhein?
The molecular formula of Rhein is C15H8O6.
What is the molecular weight of Rhein?
The molecular weight of Rhein is 284.03207 g/mol.
What are the applications of Rhein?
Rhein is used in polymer chemistry and functional materials synthesis, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Rhein (CAS 478-43-3) with custom synthesis available from milligram to...
Where can I buy Rhein?
You can request a quote for Rhein directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Rhein?
Yes, CoreyChem provides custom synthesis services for Rhein and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.