Retronecine
TL;DR: Retronecine (CAS 480-85-3) is a chemical compound with molecular formula C8H13NO2 and molecular weight 155.09464 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(1R,8R)-7-(hydroxymethyl)-2,3,5,8-tetrahydro-1H-pyrrolizin-1-ol
Also Known As: RETRONECINE, Senecifolinene, Retronecin, (+)-Retronecine, Heliotridine
Application Areas
Top 5 of 1 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C8H13NO2 |
| Molecular Weight | 155.09464 g/mol |
| XLogP | -1.3 |
| Topological Polar Surface Area (TPSA) | 43.7 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 155.09464 Da |
| Heavy Atoms | 11 |
| Complexity | 191.0 |
| Melting Point | 119-120 °C |
| Boiling Point | 80 °C @ 0.01 mm Hg |
| Vapor Pressure | 1.5X10-5 mm Hg @ 25 °C /Estimated/ |
| Solubility | Very sol in water, alc; sol in acetone; slightly sol in ether |
| SMILES | C1CN2CC=C([C@@H]2[C@@H]1O)CO |
| InChIKey | HJSJELVDQOXCHO-HTQZYQBOSA-N |
Product Description
Applications: Retronecine is used in heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Retronecine is a heterocyclic building block identified by CAS number 480-85-3 and the molecular formula C8H13NO2 and a molecular weight of 155.09 g/mol. Physically, the compound has a solubility: Very sol in water, alc; sol in acetone; slightly sol in ether. Synonyms include RETRONECINE and Senecifolinene.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Retronecine
Property Insights of Retronecine
The XLogP value of -1.3 indicates that Retronecine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. With a topological polar surface area (TPSA) of 43.7 Ų, Retronecine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Retronecine has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Retronecine?
The CAS number of Retronecine is 480-85-3.
What is the molecular formula of Retronecine?
The molecular formula of Retronecine is C8H13NO2.
What is the molecular weight of Retronecine?
The molecular weight of Retronecine is 155.09464 g/mol.
What are the applications of Retronecine?
Retronecine is used in heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical...
Where can I buy Retronecine?
You can request a quote for Retronecine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Retronecine?
Yes, CoreyChem provides custom synthesis services for Retronecine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.