Crotamiton
TL;DR: Crotamiton (CAS 483-63-6) is a chemical compound with molecular formula C13H17NO and molecular weight 203.13101 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N-ethyl-N-(2-methylphenyl)but-2-enamide
Also Known As: crotamiton, Eurax, Crotamitone, Crotalgin, Crotan
Application Areas
Top 5 of 3 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C13H17NO |
| Molecular Weight | 203.13101 g/mol |
| XLogP | 2.8 |
| Topological Polar Surface Area (TPSA) | 20.3 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 3 |
| Exact Mass | 203.13101 Da |
| Heavy Atoms | 15 |
| Complexity | 235.0 |
| Melting Point | < 25 °C |
| Boiling Point | 154 |
| Solubility | 3.53e-01 g/L |
| SMILES | CCN(C1=CC=CC=C1C)C(=O)C=CC |
| InChIKey | DNTGGZPQPQTDQF-UHFFFAOYSA-N |
Product Description
Applications: Crotamiton is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Crotamiton is a pharmaceutical intermediate identified by CAS number 483-63-6 and the molecular formula C13H17NO and a molecular weight of 203.13 g/mol. Physically, the compound has a solubility: 3.53e-01 g/L. Synonyms include crotamiton and Eurax.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Crotamiton
Property Insights of Crotamiton
The XLogP value of 2.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Crotamiton. With a topological polar surface area (TPSA) of 20.3 Ų, Crotamiton exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Crotamiton has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Crotamiton?
The CAS number of Crotamiton is 483-63-6.
What is the molecular formula of Crotamiton?
The molecular formula of Crotamiton is C13H17NO.
What is the molecular weight of Crotamiton?
The molecular weight of Crotamiton is 203.13101 g/mol.
What are the applications of Crotamiton?
Crotamiton is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Crotamiton?
You can request a quote for Crotamiton directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Crotamiton?
Yes, CoreyChem provides custom synthesis services for Crotamiton and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.