Kynurenic Acid
TL;DR: Kynurenic Acid (CAS 492-27-3) is a chemical compound with molecular formula C10H7NO3 and molecular weight 189.04259 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
4-oxo-1H-quinoline-2-carboxylic acid
Also Known As: kynurenic acid, Transtorine, 4-Hydroxyquinoline-2-carboxylic acid, Kynurenate, Quinurenic acid
Application Areas
Top 5 of 20 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C10H7NO3 |
| Molecular Weight | 189.04259 g/mol |
| XLogP | 1.3 |
| Topological Polar Surface Area (TPSA) | 66.4 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 189.04259 Da |
| Heavy Atoms | 14 |
| Complexity | 308.0 |
| Melting Point | 280 °C |
| Solubility | >28.4 [ug/mL] (The mean of the results at pH 7.4) |
| SMILES | C1=CC=C2C(=C1)C(=O)C=C(N2)C(=O)O |
| InChIKey | HCZHHEIFKROPDY-UHFFFAOYSA-N |
Product Description
Applications: Kynurenic Acid is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Kynurenic Acid is a pharmaceutical intermediate identified by CAS number 492-27-3 and the molecular formula C10H7NO3 and a molecular weight of 189.04 g/mol. Physically, the compound has a solubility: >28.4 [ug/mL] (The mean of the results at pH 7.4). Synonyms include kynurenic acid and Transtorine.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Kynurenic Acid
Property Insights of Kynurenic Acid
The XLogP value of 1.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Kynurenic Acid. The TPSA of 66.4 Ų falls within the moderate polarity range, balancing permeability and solubility for Kynurenic Acid. Following Lipinski's Rule of Five, Kynurenic Acid has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Kynurenic Acid?
The CAS number of Kynurenic Acid is 492-27-3.
What is the molecular formula of Kynurenic Acid?
The molecular formula of Kynurenic Acid is C10H7NO3.
What is the molecular weight of Kynurenic Acid?
The molecular weight of Kynurenic Acid is 189.04259 g/mol.
What are the applications of Kynurenic Acid?
Kynurenic Acid is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Kynurenic Acid?
You can request a quote for Kynurenic Acid directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Kynurenic Acid?
Yes, CoreyChem provides custom synthesis services for Kynurenic Acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.