Dihydrobenzofuran
TL;DR: Dihydrobenzofuran (CAS 496-16-2) is a chemical compound with molecular formula C8H8O and molecular weight 120.05752 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2,3-dihydro-1-benzofuran
Also Known As: 2,3-DIHYDROBENZOFURAN, Coumaran, 2,3-dihydrobenzo[b]furan, 2,3-Dihydro-1-benzofuran, Dihydrobenzofuran
Application Areas
Top 5 of 21 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C8H8O |
| Molecular Weight | 120.05752 g/mol |
| XLogP | 2.1 |
| Topological Polar Surface Area (TPSA) | 9.2 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 0 |
| Exact Mass | 120.05752 Da |
| Heavy Atoms | 9 |
| Complexity | 101.0 |
| Melting Point | -21.5 °C |
| Boiling Point | 188.00 to 189.00 °C. @ 760.00 mm Hg |
| SMILES | C1COC2=CC=CC=C21 |
| InChIKey | HBEDSQVIWPRPAY-UHFFFAOYSA-N |
Product Description
Applications: Dihydrobenzofuran is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Dihydrobenzofuran (CAS 496-16-2) is a heterocyclic building block with the molecular formula C8H8O and a molecular weight of 120.06 g/mol. Synonyms include 2,3-DIHYDROBENZOFURAN and Coumaran.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Dihydrobenzofuran
Property Insights of Dihydrobenzofuran
The XLogP value of 2.1 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Dihydrobenzofuran. With a topological polar surface area (TPSA) of 9.2 Ų, Dihydrobenzofuran exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Dihydrobenzofuran has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Dihydrobenzofuran?
The CAS number of Dihydrobenzofuran is 496-16-2.
What is the molecular formula of Dihydrobenzofuran?
The molecular formula of Dihydrobenzofuran is C8H8O.
What is the molecular weight of Dihydrobenzofuran?
The molecular weight of Dihydrobenzofuran is 120.05752 g/mol.
What are the applications of Dihydrobenzofuran?
Dihydrobenzofuran is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Dihydrobenzofuran?
You can request a quote for Dihydrobenzofuran directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Dihydrobenzofuran?
Yes, CoreyChem provides custom synthesis services for Dihydrobenzofuran and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.