2(5H)-Furanone
TL;DR: 2(5H)-Furanone (CAS 497-23-4) is a chemical compound with molecular formula C4H4O2 and molecular weight 84.021126 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2H-furan-5-one
Also Known As: 2(5H)-Furanone, Furan-2(5H)-one, Isocrotonolactone, 2-Butenolide, gamma-Crotonolactone
Application Areas
Top 5 of 19 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C4H4O2 |
| Molecular Weight | 84.021126 g/mol |
| XLogP | -0.6 |
| Topological Polar Surface Area (TPSA) | 26.3 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 0 |
| Exact Mass | 84.021126 Da |
| Heavy Atoms | 6 |
| Complexity | 93.0 |
| Melting Point | 4-5 °C |
| Boiling Point | BP: 86-87 °C at 12 mm Hg |
| Density | 1.185 mg/L at 25 °C |
| Flash Point | 101 °C (214 °F) (Closed cup) |
| Refractive Index | Index of refraction: 1.469 at 20 °C/D |
| Solubility | Soluble in water |
| SMILES | C1C=CC(=O)O1 |
| InChIKey | VIHAEDVKXSOUAT-UHFFFAOYSA-N |
Product Description
Applications: 2(5H)-Furanone is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies 2(5H)-Furanone (CAS 497-23-4) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
2(5H)-Furanone (CAS 497-23-4) is a heterocyclic building block with the molecular formula C4H4O2 and a molecular weight of 84.02 g/mol. Key physical properties include a density of 1.185 mg/L at 25 °C g/cm³, a solubility: Soluble in water. It is also known as 2(5H)-Furanone and Furan-2(5H)-one.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of 2(5H)-Furanone
Property Insights of 2(5H)-Furanone
The XLogP value of -0.6 indicates that 2(5H)-Furanone is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. With a topological polar surface area (TPSA) of 26.3 Ų, 2(5H)-Furanone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2(5H)-Furanone has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 2(5H)-Furanone?
The CAS number of 2(5H)-Furanone is 497-23-4.
What is the molecular formula of 2(5H)-Furanone?
The molecular formula of 2(5H)-Furanone is C4H4O2.
What is the molecular weight of 2(5H)-Furanone?
The molecular weight of 2(5H)-Furanone is 84.021126 g/mol.
What are the applications of 2(5H)-Furanone?
2(5H)-Furanone is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies 2(5H)-Furanone (CAS 497-23-4) with...
Where can I buy 2(5H)-Furanone?
You can request a quote for 2(5H)-Furanone directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 2(5H)-Furanone?
Yes, CoreyChem provides custom synthesis services for 2(5H)-Furanone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.