Guvacine
TL;DR: Guvacine (CAS 498-96-4) is a chemical compound with molecular formula C6H9NO2 and molecular weight 127.06333 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1,2,3,6-tetrahydropyridine-5-carboxylic acid
Also Known As: Guvacine, Guvacine hydrochloride, 1,2,5,6-tetrahydropyridine-3-carboxylic acid, 1,2,5,6-Tetrahydronicotinic acid, Lopac-G-007
Application Areas
Top 5 of 7 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C6H9NO2 |
| Molecular Weight | 127.06333 g/mol |
| XLogP | -2.5 |
| Topological Polar Surface Area (TPSA) | 49.3 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 127.06333 Da |
| Heavy Atoms | 9 |
| Complexity | 151.0 |
| Melting Point | 306 |
| Solubility | Soluble in water, and almost insoluble in 100% alcohol, ether, chloroform, and benzene. |
| SMILES | C1CNCC(=C1)C(=O)O |
| InChIKey | QTDZOWFRBNTPQR-UHFFFAOYSA-N |
Product Description
Applications: Guvacine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
A pharmaceutical intermediate supplied by CoreyChem, Guvacine (CAS 498-96-4) has the molecular formula C6H9NO2 and a molecular weight of 127.06 g/mol. Reported properties include a solubility: Soluble in water, and almost insoluble in 100% alcohol, ether, chloroform, and benzene. Synonyms include Guvacine and Guvacine hydrochloride.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Guvacine
Property Insights of Guvacine
The XLogP value of -2.5 indicates that Guvacine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. With a topological polar surface area (TPSA) of 49.3 Ų, Guvacine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Guvacine has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Guvacine?
The CAS number of Guvacine is 498-96-4.
What is the molecular formula of Guvacine?
The molecular formula of Guvacine is C6H9NO2.
What is the molecular weight of Guvacine?
The molecular weight of Guvacine is 127.06333 g/mol.
What are the applications of Guvacine?
Guvacine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Guvacine?
You can request a quote for Guvacine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Guvacine?
Yes, CoreyChem provides custom synthesis services for Guvacine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.