Proparacaine
TL;DR: Proparacaine (CAS 499-67-2) is a chemical compound with molecular formula C16H26N2O3 and molecular weight 294.19434 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-(diethylamino)ethyl 3-amino-4-propoxybenzoate
Also Known As: proparacaine, Proxymetacaine, Proximetacainum, Ophthaine, Proximetacaina
Application Areas
Top 5 of 12 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C16H26N2O3 |
| Molecular Weight | 294.19434 g/mol |
| XLogP | 2.7 |
| Topological Polar Surface Area (TPSA) | 64.8 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 10 |
| Exact Mass | 294.19434 Da |
| Heavy Atoms | 21 |
| Complexity | 295.0 |
| Melting Point | 182-183.3 °C |
| Solubility | Soluble |
| SMILES | CCCOC1=C(C=C(C=C1)C(=O)OCCN(CC)CC)N |
| InChIKey | KCLANYCVBBTKTO-UHFFFAOYSA-N |
Product Description
Applications: Proparacaine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Proparacaine is a pharmaceutical intermediate identified by CAS number 499-67-2 and the molecular formula C16H26N2O3 and a molecular weight of 294.19 g/mol. Physically, the compound has a solubility: Soluble. Synonyms include proparacaine and Proxymetacaine.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Proparacaine
Property Insights of Proparacaine
The XLogP value of 2.7 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Proparacaine. The TPSA of 64.8 Ų falls within the moderate polarity range, balancing permeability and solubility for Proparacaine. Following Lipinski's Rule of Five, Proparacaine has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Proparacaine?
The CAS number of Proparacaine is 499-67-2.
What is the molecular formula of Proparacaine?
The molecular formula of Proparacaine is C16H26N2O3.
What is the molecular weight of Proparacaine?
The molecular weight of Proparacaine is 294.19434 g/mol.
What are the applications of Proparacaine?
Proparacaine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Proparacaine?
You can request a quote for Proparacaine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Proparacaine?
Yes, CoreyChem provides custom synthesis services for Proparacaine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.