2-(alpha-Hydroxybenzyl)benzimidazole
TL;DR: 2-(alpha-Hydroxybenzyl)benzimidazole (CAS 50-97-5) is a chemical compound with molecular formula C14H12N2O and molecular weight 224.09496 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1H-benzimidazol-2-yl(phenyl)methanol
Also Known As: 1H-Benzimidazol-2-yl(phenyl)methanol, Hybendazole, Hydrobenzol, 2-Hydroxybenzylbenzimidazole, Hydrobenzole hydrochloride
Application Areas
Top 5 of 7 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C14H12N2O |
| Molecular Weight | 224.09496 g/mol |
| XLogP | 2.4 |
| Topological Polar Surface Area (TPSA) | 48.9 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 224.09496 Da |
| Heavy Atoms | 17 |
| Complexity | 253.0 |
| Solubility | >33.6 [ug/mL] (The mean of the results at pH 7.4) |
| SMILES | C1=CC=C(C=C1)C(C2=NC3=CC=CC=C3N2)O |
| InChIKey | JEAWPIKEEQZLJQ-UHFFFAOYSA-N |
Product Description
Applications: 2-(alpha-Hydroxybenzyl)benzimidazole is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies 2-(alpha-Hydroxybenzyl)benzimidazole (CAS 50-97-5) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
2-(alpha-Hydroxybenzyl)benzimidazole is a pharmaceutical intermediate identified by CAS number 50-97-5 and the molecular formula C14H12N2O and a molecular weight of 224.09 g/mol. Physically, the compound has a solubility: >33.6 [ug/mL] (The mean of the results at pH 7.4). It is also known as 1H-Benzimidazol-2-yl(phenyl)methanol and Hybendazole.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of 2-(alpha-Hydroxybenzyl)benzimidazole
Property Insights of 2-(alpha-Hydroxybenzyl)benzimidazole
The XLogP value of 2.4 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2-(alpha-Hydroxybenzyl)benzimidazole. With a topological polar surface area (TPSA) of 48.9 Ų, 2-(alpha-Hydroxybenzyl)benzimidazole exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-(alpha-Hydroxybenzyl)benzimidazole has 2 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 2-(alpha-Hydroxybenzyl)benzimidazole?
The CAS number of 2-(alpha-Hydroxybenzyl)benzimidazole is 50-97-5.
What is the molecular formula of 2-(alpha-Hydroxybenzyl)benzimidazole?
The molecular formula of 2-(alpha-Hydroxybenzyl)benzimidazole is C14H12N2O.
What is the molecular weight of 2-(alpha-Hydroxybenzyl)benzimidazole?
The molecular weight of 2-(alpha-Hydroxybenzyl)benzimidazole is 224.09496 g/mol.
What are the applications of 2-(alpha-Hydroxybenzyl)benzimidazole?
2-(alpha-Hydroxybenzyl)benzimidazole is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies...
Where can I buy 2-(alpha-Hydroxybenzyl)benzimidazole?
You can request a quote for 2-(alpha-Hydroxybenzyl)benzimidazole directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 2-(alpha-Hydroxybenzyl)benzimidazole?
Yes, CoreyChem provides custom synthesis services for 2-(alpha-Hydroxybenzyl)benzimidazole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.