Nordihydroguaretic acid
TL;DR: Nordihydroguaretic acid (CAS 500-38-9) is a chemical compound with molecular formula C18H22O4 and molecular weight 302.1518 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
4-[4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol
Also Known As: NORDIHYDROGUAIARETIC ACID, NDGA, Masoprocol, Actinex, Dihydronorguaiaretic acid
Application Areas
Top 5 of 8 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C18H22O4 |
| Molecular Weight | 302.1518 g/mol |
| XLogP | 4.3 |
| Topological Polar Surface Area (TPSA) | 80.9 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Exact Mass | 302.1518 Da |
| Heavy Atoms | 22 |
| Complexity | 303.0 |
| SMILES | CC(CC1=CC(=C(C=C1)O)O)C(C)CC2=CC(=C(C=C2)O)O |
| InChIKey | HCZKYJDFEPMADG-UHFFFAOYSA-N |
Product Description
Applications: Nordihydroguaretic acid is used in pharmaceutical synthesis routes and API production, as well as complex organic molecule assembly across discovery and process chemistry. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
A pharmaceutical intermediate supplied by CoreyChem, Nordihydroguaretic acid (CAS 500-38-9) has the molecular formula C18H22O4 and a molecular weight of 302.15 g/mol. Synonyms include NORDIHYDROGUAIARETIC ACID and NDGA.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Nordihydroguaretic acid
Property Insights of Nordihydroguaretic acid
The XLogP value of 4.3 indicates that Nordihydroguaretic acid is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 80.9 Ų falls within the moderate polarity range, balancing permeability and solubility for Nordihydroguaretic acid. Following Lipinski's Rule of Five, Nordihydroguaretic acid has 4 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Nordihydroguaretic acid?
The CAS number of Nordihydroguaretic acid is 500-38-9.
What is the molecular formula of Nordihydroguaretic acid?
The molecular formula of Nordihydroguaretic acid is C18H22O4.
What is the molecular weight of Nordihydroguaretic acid?
The molecular weight of Nordihydroguaretic acid is 302.1518 g/mol.
What are the applications of Nordihydroguaretic acid?
Nordihydroguaretic acid is used in pharmaceutical synthesis routes and API production, as well as complex organic molecule assembly across discovery and process chemistry. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Nordihydroguaretic acid?
You can request a quote for Nordihydroguaretic acid directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Nordihydroguaretic acid?
Yes, CoreyChem provides custom synthesis services for Nordihydroguaretic acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.